4541080

Epredia™ Lab Vision™ CDX2 Rabbit Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ CDX2, Rabbit Monoclonal Antibody.

Manufacturer: Fischer Scientific

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Antigen

anti-CDX2

Applications

Immunohistochemistry

Conjugate

Unconjugated

Immunogen

A synthetic peptide corresponding to residues near the N-terminus of human CDX2

Clone

EPR2764Y

Classification

Monoclonal

Host Species

Rabbit

Primary or Secondary

Primary

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Description

  • The caudal-related homeodomain protein2 (CDX2) is a transcription factor shown to play a role in the development of small and large intestine in mammals and in the differentiation of intestinal epithelial cells
  • It has been shown that CDX2 protein detection by IHC coorelates with RNA transcript levels
  • In studies using 745 cancers from many anatomic sites, colonic adenocarcinomas demonstrated strong staining in 90% of the cases, while adenocarcinomas of the stomach, esophagus and ovary showed extensive staining in only 30% of the cases
  • Stains of CDX2 and Villin are useful markers in differntial diagnosis of bladder adenocarcinoma and secondary colorectal adenocarcinoma
  • Host Species: Rabbit Clone: EPR2764Y Species Reactivity: Human
  • Others not tested
  • Ig Isotype: Rabbit IgG Epitope: not determined Immunogen: A synthetic peptide corresponding to residues near the N-terminus of human CDX2 Molecular Weight: 40 kDa Positive Control: Colon carcinomas Cellular Localization: Nuclear with occasional cytoplasmic staining on colon carcinoma Recommended for: Immunohistochemistry (Formalin/paraffin)

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Antigen:
anti-CDX2

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Immunogen:
A synthetic peptide corresponding to residues near the N-terminus of human CDX2

Clone:
EPR2764Y

Classification:
Monoclonal

Host Species:
Rabbit

Primary or Secondary:
Primary

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4541095

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Antigen:
Chromogranin A

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Immunogen:
Recombinant protein encoding human chromogranin A

Clone:
SP12

Classification:
Monoclonal

Host Species:
Rabbit

Primary or Secondary:
Primary

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4541099

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Antigen:
Chromogranin A Ab-3

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Immunogen:
Human pheochromocytoma

Clone:
LK2H10 + PHE5

Classification:
Monoclonal

Host Species:
Mouse

Primary or Secondary:
Primary

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