4543255

Epredia™ Lab Vision™ p504s/AMACR, Rabbit Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ p504s/AMACR, Rabbit Monoclonal Antibody.

Manufacturer: Fischer Scientific

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Antigen

p504s/AMACR

Applications

Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Regulatory Status

ASR

Immunogen

Human p504s/AMACR polypeptide

Clone

13H4

Classification

Monoclonal

Host Species

Rabbit

Research Discipline

Cancer and Tumor Biology

Primary or Secondary

Primary

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Description

  • Alpha methylacyl-CoA-racemase (AMACR), also known as p504s is an enzyme involved in the metabolism of branched-chain fatty acids
  • p504s is expressed in various normal tissues and carcinomas, while it is overexpressed over 30-fold in prostate carcinoma compared to benign glandular tissues 1
  • When p504s is overexpressed in atypical glands without basal cells, it establishes a diagnosis of prostatic carcinoma
  • High-grade prostatic intraepithelial neoplasia, atypical adenomatous hyperplasia and urothelial carcinoma may also express p504s
  • Host Species: Rabbit Clone: 13H4 Isotype: IgG Species Reactivity: Human
  • Others not tested
  • Immunogen: Human p504s/AMACR polypeptide Molecular Weight: ∽45 kDa Positive Control: Prostate carcinoma Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin)

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Antigen:
p504s/AMACR

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
ASR

Immunogen:
Human p504s/AMACR polypeptide

Clone:
13H4

Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
Cancer and Tumor Biology

Primary or Secondary:
Primary

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Antigen:
Collagen II Ab-2

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
__

Regulatory Status:
RUO

Immunogen:
A purified preparation of lathyritic type II collagen from embryonic chicken sternum

Clone:
2B1.5

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Extracellular Matrix

Primary or Secondary:
Primary

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Antigen:
Collagen VII Ab-1

Applications:
Immunofluorescence, Immunohistochemistry (Frozen)

Conjugate:
Unconjugated

Regulatory Status:
RUO

Immunogen:
Insoluble fractions of human neonatal foreskin epidermal cells

Clone:
LH7.2

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
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Primary or Secondary:
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Antigen:
Collagen II Ab-1

Applications:
Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Immunogen:
A purified preparation of lathyritic type II collagen from embryonic chicken sternum

Clone:
5B2.5

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Extracellular Matrix

Primary or Secondary:
Primary