4544016

Epredia™ Lab Vision™ Cytokeratin 17 Ab-1, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments with Epredia™ Cytokeratin 17 Ab-1, Mouse Monoclonal Antibody.

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Cytokeratin 17 Ab-1

Applications

Immunofluorescence, Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Regulatory Status

IVD

Target Species

Human, Rat

Isotype

IgG2b κ

Clone

E3

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cytoskeletal Protein

Immunogen

Keratin preparation from rat enterocytes

Primary or Secondary

Primary

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Description

  • The type I keratin 17 (K17) shows a peculiar localization in human epithelial appendages including hair follicles, which undergo a growth cycle throughout adult life
  • Additionally K17 is induced, along with K6 and K16, early after acute injury to human skin
  • Predominant expression of K17 and the frequent expression of K8 and K19, with little K6/K16 and K1/K10 expression are the characteristic features of basal cell carcinomas (BCC), suggesting that BCC is differentiated towards undifferentiated follicular epithelia, most probably hair bulge cells
  • Host Species: Mouse Clone: E3 Isotype: IgG2b/κ Species Reactivity: Human and Rat
  • Others not known
  • Epitope: Not determined Immunogen: Cytokeratin preparation from rat enterocytes Molecular Weight: 46 kDa Positive Control: Squamous cell CA, Skin Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin) Immunofluorescence

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Antigen:
Cytokeratin 17 Ab-1

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Target Species:
Human, Rat

Isotype:
IgG2b κ

Clone:
E3

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cytoskeletal Protein

Immunogen:
Keratin preparation from rat enterocytes

Primary or Secondary:
Primary

Img

Fischer Scientific

4544018

Ensure accurate, reproducible resul...


Antigen:
Cytokeratin 18 Ab-1

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
__

Regulatory Status:
IVD

Target Species:
Human

Isotype:
IgG1

Clone:
DC10

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cytoskeletal Protein

Immunogen:
Human breast cancer PMC 42 cells

Primary or Secondary:
Primary

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4544020

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Antigen:
Cytokeratin 18

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Target Species:
__

Isotype:
__

Clone:
E431-1

Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
Cancer and Tumor Biology

Immunogen:
A synthetic peptide corresponding to residues of the human CK18

Primary or Secondary:
Primary

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Fischer Scientific

4544020

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Antigen:
Cytokeratin 18

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Target Species:
__

Isotype:
__

Clone:
E431-1

Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
Cancer and Tumor Biology

Immunogen:
A synthetic peptide corresponding to residues of the human CK18

Primary or Secondary:
Primary