4544034

Epredia™ Lab Vision™ Cytokeratin 5 Ab-1, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ Cytokeratin 5 Ab-1, Mouse Monoclonal Antibody.

Manufacturer: Fischer Scientific

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Antigen

Cytokeratin 5 Ab-1

Applications

Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Regulatory Status

IVD

Target Species

Human

Isotype

IgG2a κ

Clone

XM26

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cytoskeletal Protein

Immunogen

Recombinant protein corresponding to C-terminal 103 aa of cytokeratin 5

Primary or Secondary

Primary

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Description

  • Twenty human keratins are divided into acidic (pI <5.7) and basic (pI >6.0) subfamilies
  • Members of the acidic and basic subfamilies are found together in pairs
  • The composition of keratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state
  • Many studies have shown the usefulness of keratins as markers in cancer research and tumor identification
  • Point mutations in cytokeratin5 gene can cause various types of epidermolysis bullosa simplex
  • It is expressed in most epithelial and biphasic mesotheliomas
  • Host Species: Mouse Clone: XM26 Isotype: IgG1/κ Species Reactivity: Human
  • Others not known
  • Epitope: C-terminal Immunogen: Recombinant protein corresponding to C-terminal 103 aa of cytokeratin 5 Molecular Weight: 58 kDa Positive Control: Mesothelioma Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin)

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Fischer Scientific

4544034

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Antigen:
Cytokeratin 5 Ab-1

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Target Species:
Human

Isotype:
IgG2a κ

Clone:
XM26

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cytoskeletal Protein

Immunogen:
Recombinant protein corresponding to C-terminal 103 aa of cytokeratin 5

Primary or Secondary:
Primary

Img

Fischer Scientific

4544036

Ensure accurate, reproducible resul...


Antigen:
Cytokeratin 5

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Target Species:
__

Isotype:
__

Clone:
EP1601Y

Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
Cancer and Tumor Biology

Immunogen:
A synthetic peptide corresponding to residues on the C-term of human CK5

Primary or Secondary:
Primary

Img

Fischer Scientific

4544036

Ensure accurate, reproducible resul...


Antigen:
Cytokeratin 5

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Target Species:
__

Isotype:
__

Clone:
EP1601Y

Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
Cancer and Tumor Biology

Immunogen:
A synthetic peptide corresponding to residues on the C-term of human CK5

Primary or Secondary:
Primary

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Fischer Scientific

4544042

Obtain accurate, reproducible resul...


Antigen:
Cytokeratin 8/18 Ab-1

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Target Species:
__

Isotype:
__

Clone:
5D3

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cytoskeletal Protein

Immunogen:
Cytokeratins purified from breast cancer MCF-7 cells

Primary or Secondary:
Primary