4545754

Epredia™ Lab Vision™ CD38 Ab-3, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ CD38 Ab-3, Mouse Monoclonal Antibody.

Manufacturer: Fischer Scientific

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Antigen

CD38 Ab-3

Applications

Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1

Clone

38C03; same as SPC32

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Adhesion

Immunogen

Recombinant protein encoding the extracellular domain of human CD38

Primary or Secondary

Primary

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Description

  • CD38 is a single chain type II integral transmembrane protein, which is highly expressed on thymocytes
  • It is also present on activated T cells and terminally differentiated B cells (plasma cells)
  • Other reactive cells include NK cells, monocytes, macrophages, and dendritic cells
  • CD38 may be detected on cells from multiple myeloma, ALL (B and T) and some AML
  • It is, however, not found on most mature resting peripheral lymphocytes
  • CD38 functions as a multicatalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor
  • Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e
  • identification of myelomas), and as a marker for activated B and T cells
  • Host Species: Mouse Clone: 38C03; same as SPC32 Isotype: IgG1 Species Reactivity: Human
  • Others not tested
  • Epitope: Extracellular Immunogen: Recombinant protein encoding the extracellular domain of human CD38 Molecular Weight: 45 kDa Positive Control: Tonsil Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting (Not suitable) Note: USA: RUO; Int'l: RUO

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Antigen:
CD38 Ab-3

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1

Clone:
38C03; same as SPC32

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Adhesion

Immunogen:
Recombinant protein encoding the extracellular domain of human CD38

Primary or Secondary:
Primary

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Antigen:
GCDFP-15 (Gross Cystic Disease Fluid Protein-15) Ab-1

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Target Species:
__

Isotype:
__

Clone:
23A3

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cancer and Tumor Biology

Immunogen:
Recombinant protein encoding the excreted domain of human GCDFP15

Primary or Secondary:
Primary

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Antigen:
GFAP (Glial Fibrillary Acidic Protein)

Applications:
Immunofluorescence

Conjugate:
Unconjugated

Regulatory Status:
IVD

Target Species:
Chicken, Human, Porcine, Rat

Isotype:
IgG1

Clone:
ASTRO6

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Neuroscience

Immunogen:
Glial Fibrillary Acidic Protein

Primary or Secondary:
Primary

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Antigen:
GFAP (Glial Fibrillary Acidic Protein)

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Bovine, Chicken, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Rat

Isotype:
IgG

Clone:
__

Classification:
Polyclonal

Host Species:
Rabbit

Research Discipline:
Neuroscience

Immunogen:
GFAP isolated from cow spinal cord

Primary or Secondary:
Primary