4547013
CD117/c-Kit/SCF-Receptor Rabbit Polyclonal Antibody, Epredia™
Optimize staining of formalin-fixed, paraffin-embedded tissues with Epredia™ CD117/c-Kit/SCF-Receptor, Rabbit Polyclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
CD117/c-Kit/SCF-Receptor
Classification
Polyclonal
Host Species
Rabbit
Immunogen
A synthetic peptide from the cytoplasmic domain of human CD117 / c-kit protein
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Regulatory Status
IVD
Primary or Secondary
Primary
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Description
- Recognizes a protein of 145kDa, which is identified as CD117/p145kit
- This rabbit polyclonal antibody does not interfere with the binding of SCF to c-kit
- It precipitates both the unoccupied as well as the occupied form of c-kit
- The binding of the stem cell factor (SCF) to the c-kit-encoded receptor tyrosine kinase (Type III) stimulates a variety of biochemical responses that culminate in cellular proliferation, migration, or survival
- C-kit plays an important role in hematopoiesis, melanogenesis, and gametogenesis
- This antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues
- Host Species: Rabbit Isotype: IgG Species Reactivity: Human and Dog
- Others not tested Epitope: Cytoplasmic domain Immunogen: A synthetic peptide from the cytoplasmic domain of human CD117/c-kit protein Molecular Weight: 145 kDa Positive Control: Stromal tumor, skin or tonsil Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin)
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Antigen: CD117/c-Kit/SCF-Receptor
Classification: Polyclonal
Host Species: Rabbit
Immunogen: A synthetic peptide from the cytoplasmic domain of human CD117 / c-kit protein
Applications: Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Regulatory Status: IVD
Primary or Secondary: Primary
Antigen:
CD117/c-Kit/SCF-Receptor
Classification:
Polyclonal
Host Species:
Rabbit
Immunogen:
A synthetic peptide from the cytoplasmic domain of human CD117 / c-kit protein
Applications:
Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Regulatory Status:
IVD
Primary or Secondary:
Primary
Antigen: CD137 Ab-1
Classification: Monoclonal
Host Species: Mouse
Immunogen: Ectodomain of human 4-1BB recombinant protein
Applications: Flow Cytometry, Immunofluorescence
Conjugate: __
Regulatory Status: RUO
Primary or Secondary: Primary
Antigen:
CD137 Ab-1
Classification:
Monoclonal
Host Species:
Mouse
Immunogen:
Ectodomain of human 4-1BB recombinant protein
Applications:
Flow Cytometry, Immunofluorescence
Conjugate:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary
Antigen: CD137 Ab-1
Classification: Monoclonal
Host Species: Mouse
Immunogen: Ectodomain of human 4-1BB recombinant protein
Applications: Flow Cytometry, Immunofluorescence
Conjugate: __
Regulatory Status: RUO
Primary or Secondary: Primary
Antigen:
CD137 Ab-1
Classification:
Monoclonal
Host Species:
Mouse
Immunogen:
Ectodomain of human 4-1BB recombinant protein
Applications:
Flow Cytometry, Immunofluorescence
Conjugate:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary
Antigen: CD137 Ab-1
Classification: Monoclonal
Host Species: Mouse
Immunogen: Ectodomain of human 4-1BB recombinant protein
Applications: Flow Cytometry, Immunofluorescence
Conjugate: __
Regulatory Status: RUO
Primary or Secondary: Primary
Antigen:
CD137 Ab-1
Classification:
Monoclonal
Host Species:
Mouse
Immunogen:
Ectodomain of human 4-1BB recombinant protein
Applications:
Flow Cytometry, Immunofluorescence
Conjugate:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary