4547915

HER-3/c-erbB-3 Ab-4 Mouse Monoclonal Antibody, Epredia™

Epredia™ HER-3/c-erbB-3 Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

HER-3/c-erbB-3 Ab-4

Applications

Flow Cytometry, Immunofluorescence, Immunoprecipitation

Form

Concentrated

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a

Clone

H3.90.6; same as Ab90

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Oncogenesis

Immunogen

Extracellular fragment of recombinant human c-erbB-3/HER-3 oncoprotein

Primary or Secondary

Primary

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Description

  • c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors
  • It binds to ligands in the heregulin family
  • c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon
  • Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents
  • Host Species: Mouse Clone: H3.90.6; same as Ab90 Isotype: IgG2a Species Reactivity: Human
  • Others not tested
  • Epitope: Extracellular domain Immunogen: Extracellular fragment of recombinant human HER-3/c-erbB-3 oncoprotein Molecular Weight: 185kDa Positive Control: T47D cells Cellular Localization: Cytoplasmic and membrane Recommended for: Western Blotting (Not suitable) Immunofluorescence Immunoprecipitation Flow Cytometry Effect on Heregulin (NDF) Binding (Noninhibitory) Effect on Tumor Growth (Noninhibitory) Note: USA: RUO; Int'l: RUO

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Antigen:
HER-3/c-erbB-3 Ab-4

Applications:
Flow Cytometry, Immunofluorescence, Immunoprecipitation

Form:
Concentrated

Regulatory Status:
RUO

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Human

Isotype:
IgG2a

Clone:
H3.90.6; same as Ab90

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Monoclonal

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Mouse

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Oncogenesis

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Extracellular fragment of recombinant human c-erbB-3/HER-3 oncoprotein

Primary or Secondary:
Primary

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