4548971
IGF-1R (α-subunit) Ab-1 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ IGF-1R (α-Subunit) Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
IGF-1R (alpha-Subunit) Ab-1
Applications
Immunoprecipitation
Form
Concentrated
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1
Clone
24-31
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Neuroscience
Immunogen
IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA
Primary or Secondary
Primary
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Description
- IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of α- and Β-subunits, which are disulfide-linked in a Β-α-α-Β configuration in the mature receptor
- The α-subunit is completely extracellular, while the Β-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity
- Host Species: Mouse Clone: 24-31 Isotype: IgG1 Species Reactivity: Human
- Weakly reacts with Rabbit
- Does not react with rat
- Pig unknown
- Epitope: aa 283-440 (exon 4-6) Immunogen: IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA Molecular Weight: 125kDa Positive Control: Placenta or Breast CA Cellular Localization: Membrane Recommended for: Western Blotting (Not suitable) Immunoprecipitation ELISA Acts as a Weak IGF-like Agonist in Bioassays (Thymidine incorporation into DNA) Does Not Significantly Inhibit IGF-1 Binding Note: USA: RUO; Int'l: RUO
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Antigen: IGF-1R (alpha-Subunit) Ab-1
Applications: Immunoprecipitation
Form: Concentrated
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1
Clone: 24-31
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Neuroscience
Immunogen: IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA
Primary or Secondary: Primary
Antigen:
IGF-1R (alpha-Subunit) Ab-1
Applications:
Immunoprecipitation
Form:
Concentrated
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1
Clone:
24-31
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Neuroscience
Immunogen:
IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA
Primary or Secondary:
Primary
Antigen: IgA (alpha-Heavy Chain) Ab-2
Applications: Immunohistochemistry (Paraffin)
Form: __
Regulatory Status: IVD
Target Species: Human
Isotype: IgG
Clone: __
Classification: Polyclonal
Host Species: Rabbit
Research Discipline: Immunoglobulins
Immunogen: IgA isolated from a pool of normal human sera
Primary or Secondary: Primary
Antigen:
IgA (alpha-Heavy Chain) Ab-2
Applications:
Immunohistochemistry (Paraffin)
Form:
__
Regulatory Status:
IVD
Target Species:
Human
Isotype:
IgG
Clone:
__
Classification:
Polyclonal
Host Species:
Rabbit
Research Discipline:
Immunoglobulins
Immunogen:
IgA isolated from a pool of normal human sera
Primary or Secondary:
Primary
Antigen: __
Applications: __
Form: __
Regulatory Status: __
Target Species: __
Isotype: __
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