4541963
Epidermal Growth Factor Receptor/EGFR Ab-2 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results in immunoprecipitation experiments with Epredia™ Epidermal Growth Factor Receptor/EGFR Ab-2, Mouse Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
Epidermal Growth Factor Receptor/EGFR Ab-2
Applications
Immunoprecipitation
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
EGFR Family
Immunogen
Purified EGFR from A431 cells
Primary or Secondary
Primary
Clone
225
Classification
Monoclonal
Form
Concentrated
Regulatory Status
RUO
Target Species
Human, Non-human Primate
Isotype
IgG1
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Description
- EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4
- It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin
- EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium
- It is predominantly present in squamous cell carcinomas
- Host Species: Mouse Clone: 225 Isotype: IgG1 Species Reactivity: Human, Chimpanzee and Monkey
- Does not react with mouse and rat
- Others not known
- Epitope: Extracellular domain Immunogen: Purified EGFR from A431 cells Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant) Positive Control: A431 cells Cellular Localization: Membrane Recommended for: Immunoprecipitation (Native only) Blocks EGF/TGFα-Induced Activation of EGFR Arrests Tumor Growth in vivo Inhibits Binding of Ab-1 (clone 528) to EGFR Note: USA: RUO; Int'l: RUO
Compare Similar Items
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Antigen: Epidermal Growth Factor Receptor/EGFR Ab-2
Applications: Immunoprecipitation
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: EGFR Family
Immunogen: Purified EGFR from A431 cells
Primary or Secondary: Primary
Clone: 225
Classification: Monoclonal
Form: Concentrated
Regulatory Status: RUO
Target Species: Human, Non-human Primate
Isotype: IgG1
Antigen:
Epidermal Growth Factor Receptor/EGFR Ab-2
Applications:
Immunoprecipitation
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
EGFR Family
Immunogen:
Purified EGFR from A431 cells
Primary or Secondary:
Primary
Clone:
225
Classification:
Monoclonal
Form:
Concentrated
Regulatory Status:
RUO
Target Species:
Human, Non-human Primate
Isotype:
IgG1
Antigen: Estrogen Receptor Ab-11
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Steroids Hormones and Growth Factors
Immunogen: Recombinant human estrogen receptor protein
Primary or Secondary: Primary
Clone: 1D5
Classification: Monoclonal
Form: __
Regulatory Status: ASR, IVD
Target Species: Human, Mouse, Non-human Primate, Rat
Isotype: IgG2a κ
Antigen:
Estrogen Receptor Ab-11
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Steroids Hormones and Growth Factors
Immunogen:
Recombinant human estrogen receptor protein
Primary or Secondary:
Primary
Clone:
1D5
Classification:
Monoclonal
Form:
__
Regulatory Status:
ASR, IVD
Target Species:
Human, Mouse, Non-human Primate, Rat
Isotype:
IgG2a κ
Antigen: Estrogen Receptor Ab-12
Applications: Immunoprecipitation
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Steroids Hormones and Growth Factors
Immunogen: Recombinant full length estrogen receptor protein
Primary or Secondary: Primary
Clone: 6F11
Classification: Monoclonal
Form: __
Regulatory Status: RUO
Target Species: Human, Rat
Isotype: IgG1
Antigen:
Estrogen Receptor Ab-12
Applications:
Immunoprecipitation
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Steroids Hormones and Growth Factors
Immunogen:
Recombinant full length estrogen receptor protein
Primary or Secondary:
Primary
Clone:
6F11
Classification:
Monoclonal
Form:
__
Regulatory Status:
RUO
Target Species:
Human, Rat
Isotype:
IgG1
Antigen: Estrogen Receptor Ab-12
Applications: Immunoprecipitation
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Steroids Hormones and Growth Factors
Immunogen: Recombinant full length estrogen receptor protein
Primary or Secondary: Primary
Clone: 6F11
Classification: Monoclonal
Form: __
Regulatory Status: RUO
Target Species: Human, Rat
Isotype: IgG1
Antigen:
Estrogen Receptor Ab-12
Applications:
Immunoprecipitation
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Steroids Hormones and Growth Factors
Immunogen:
Recombinant full length estrogen receptor protein
Primary or Secondary:
Primary
Clone:
6F11
Classification:
Monoclonal
Form:
__
Regulatory Status:
RUO
Target Species:
Human, Rat
Isotype:
IgG1