4543453
HER-2/c-erbB-2/neu Ab-5 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ HER-2/c-erbB-2/neu Ab-5, Mouse Monoclonal Antibody.
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
HER-2/c-erbB-2/neu Ab-5
Applications
Immunofluorescence, Immunoprecipitation
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
EGFR Family
Immunogen
Intact SKBR-3 breast cancer cells
Primary or Secondary
Primary
Clone
N24
Classification
Monoclonal
Form
Concentrated
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1
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Description
- c-erbB-2 is a receptor tyrosine kinase
- It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites
- Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein Host Species: Mouse Clone: N24 Isotype: IgG1 Species Reactivity: Human
- Does not react with mouse and rat
- Others not tested
- Epitope: Extracellular domain Immunogen: Intact SKBR-3 breast cancer cells Molecular Weight: 185 kDa Positive Control: SKBR-3 cells, or Breast CA Cellular Localization: Membrane Recommended for: Immunofluorescence Immunoprecipitation Accelerates (∽50%) HER-2 Internalization Inhibits (∽80%) Tumorigenic Cell Growth Note: USA: RUO; Int'l: RUO
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Antigen: HER-2/c-erbB-2/neu Ab-5
Applications: Immunofluorescence, Immunoprecipitation
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: EGFR Family
Immunogen: Intact SKBR-3 breast cancer cells
Primary or Secondary: Primary
Clone: N24
Classification: Monoclonal
Form: Concentrated
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1
Antigen:
HER-2/c-erbB-2/neu Ab-5
Applications:
Immunofluorescence, Immunoprecipitation
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
EGFR Family
Immunogen:
Intact SKBR-3 breast cancer cells
Primary or Secondary:
Primary
Clone:
N24
Classification:
Monoclonal
Form:
Concentrated
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1
Antigen: HER-2/c-erbB-2/neu
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: __
Immunogen: A synthetic peptide corresponding to the c-terminus of human Her2
Primary or Secondary: Primary
Clone: EP1045Y
Classification: __
Form: __
Regulatory Status: __
Target Species: __
Isotype: __
Antigen:
HER-2/c-erbB-2/neu
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
__
Immunogen:
A synthetic peptide corresponding to the c-terminus of human Her2
Primary or Secondary:
Primary
Clone:
EP1045Y
Classification:
__
Form:
__
Regulatory Status:
__
Target Species:
__
Isotype:
__
Antigen: Filaggrin Ab-1
Applications: Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Cytoskeletal Protein
Immunogen: Recombinant filaggrin protein
Primary or Secondary: Primary
Clone: FLG01
Classification: Monoclonal
Form: __
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
Filaggrin Ab-1
Applications:
Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cytoskeletal Protein
Immunogen:
Recombinant filaggrin protein
Primary or Secondary:
Primary
Clone:
FLG01
Classification:
Monoclonal
Form:
__
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: Cyclin D1/Bcl-1
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: Cell Cycle
Immunogen: A synthetic peptide from C-terminus of human cyclin D1
Primary or Secondary: Primary
Clone: SP4
Classification: Monoclonal
Form: __
Regulatory Status: IVD
Target Species: __
Isotype: __
Antigen:
Cyclin D1/Bcl-1
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
Cell Cycle
Immunogen:
A synthetic peptide from C-terminus of human cyclin D1
Primary or Secondary:
Primary
Clone:
SP4
Classification:
Monoclonal
Form:
__
Regulatory Status:
IVD
Target Species:
__
Isotype:
__