4541944

Epidermal Growth Factor Receptor/EGFR Ab-5 Mouse Monoclonal Antibody, Epredia™

Obtain accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence, immunoprecipitation and flow cytometry experiments.

Manufacturer: Fischer Scientific

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Antigen

Epidermal Growth Factor Receptor/EGFR Ab-5

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

EGFR Family

Immunogen

HC2 20 d2 cells

Primary or Secondary

Primary

Clone

H11

Classification

Monoclonal

Form

Concentrated

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4
  • It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin
  • EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium
  • It is predominantly present in squamous cell carcinomas
  • Host Species: Mouse Clone: H11 Isotype: IgG1/κ Species Reactivity: Human
  • Does not react with mouse and rat
  • Others not known
  • Epitope: Extracellular domain Immunogen: HC2 20 d2 cells Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant) Positive Control: A431 cells, Placenta or Squamous cell CA Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunofluorescence Immunoprecipitation (Native only) Flow Cytometry Note: USA: RUO; Int'l: RUO

Compare Similar Items

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Fischer Scientific

4541944

Obtain accurate, reproducible resul...


Antigen:
Epidermal Growth Factor Receptor/EGFR Ab-5

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
EGFR Family

Immunogen:
HC2 20 d2 cells

Primary or Secondary:
Primary

Clone:
H11

Classification:
Monoclonal

Form:
Concentrated

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

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4541948

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Antigen:
Epithelial Membrane Antigen/EMA Ab-3

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Oncogenesis

Immunogen:
Delipidated extract of human milk fat globule membranes

Primary or Secondary:
Primary

Clone:
E29

Classification:
Monoclonal

Form:
__

Regulatory Status:
IVD

Target Species:
Human

Isotype:
IgG2a κ

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4541961

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Antigen:
Epstein-Barr Virus/LMP Ab-1

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Infectious Disease

Immunogen:
EBV-encoded recombinant latent membrane protein

Primary or Secondary:
Primary

Clone:
CS1+CS2+CS3+CS4

Classification:
Monoclonal

Form:
__

Regulatory Status:
ASR, IVD

Target Species:
__

Isotype:
IgG2a κ

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Antigen:
Epidermal Growth Factor Receptor/EGFR Ab-2

Applications:
Immunoprecipitation

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
EGFR Family

Immunogen:
Purified EGFR from A431 cells

Primary or Secondary:
Primary

Clone:
225

Classification:
Monoclonal

Form:
Concentrated

Regulatory Status:
RUO

Target Species:
Human, Non-human Primate

Isotype:
IgG1