4542560

Estrogen Receptor Ab-11 Mouse Monoclonal Antibody, Epredia™

Obtain accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Estrogen Receptor Ab-11, Mouse Monoclonal Antibody.

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Estrogen Receptor Ab-11

Applications

Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Regulatory Status

ASR, IVD

Target Species

Human, Mouse, Non-human Primate, Rat

Isotype

IgG2a κ

Clone

1D5

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Steroids Hormones and Growth Factors

Immunogen

Recombinant human estrogen receptor protein

Primary or Secondary

Primary

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Description

  • Description The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition
  • The ER is an important regulator of growth and differentiation in the mammary gland
  • Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g
  • tamoxifen) therapy
  • Host Species: Mouse Clone: 1D5 Isotype: IgG1/κ Species Reactivity: Human, Monkey, Mouse and Rat
  • Others not known
  • Epitope: N-terminal domain Immunogen: Recombinant human estrogen receptor protein Molecular Weight: 67 kDa Positive Control: MCF-7 cells, Breast CA Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting

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Fischer Scientific

4542560

Obtain accurate, reproducible resul...


Antigen:
Estrogen Receptor Ab-11

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Regulatory Status:
ASR, IVD

Target Species:
Human, Mouse, Non-human Primate, Rat

Isotype:
IgG2a κ

Clone:
1D5

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Steroids Hormones and Growth Factors

Immunogen:
Recombinant human estrogen receptor protein

Primary or Secondary:
Primary

Img

Fischer Scientific

4542562

Ensure accurate, reproducible resul...


Antigen:
Estrogen Receptor Ab-12

Applications:
Immunoprecipitation

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Human, Rat

Isotype:
IgG1

Clone:
6F11

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Steroids Hormones and Growth Factors

Immunogen:
Recombinant full length estrogen receptor protein

Primary or Secondary:
Primary

Img

Fischer Scientific

4542562

Ensure accurate, reproducible resul...


Antigen:
Estrogen Receptor Ab-12

Applications:
Immunoprecipitation

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Human, Rat

Isotype:
IgG1

Clone:
6F11

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Steroids Hormones and Growth Factors

Immunogen:
Recombinant full length estrogen receptor protein

Primary or Secondary:
Primary

Img

Fischer Scientific

4542568

Epredia™ Estrogen Receptor Ab-17, R...


Antigen:
Estrogen Receptor Ab-17

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Bovine, Human, Mouse, Porcine, Rabbit, Rat

Isotype:
IgG

Clone:
__

Classification:
Polyclonal

Host Species:
Rabbit

Research Discipline:
Steroids Hormones and Growth Factors

Immunogen:
A synthetic peptide from the N-terminus of human estrogen receptor, alpha protein

Primary or Secondary:
Primary