4542562

Epredia™ Lab Vision™ Estrogen Receptor Ab-12, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

Manufacturer: Fischer Scientific

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Antigen

Estrogen Receptor Ab-12

Applications

Immunoprecipitation

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Human, Rat

Isotype

IgG1

Clone

6F11

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Steroids Hormones and Growth Factors

Immunogen

Recombinant full length estrogen receptor protein

Primary or Secondary

Primary

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Description

  • Description The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition
  • The ER is an important regulator of growth and differentiation in the mammary gland
  • Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g
  • tamoxifen) therapy
  • Host Species: Mouse Clone: 6F11 Isotype: IgG1 Species Reactivity: Human and Rat
  • Others not known
  • Immunogen: Recombinant full-length estrogen receptor protein Molecular Weight: 67 kDa Positive Control: MCF-7 cells, Breast CA Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunoprecipitation (Denatured verified) Note: USA: RUO; Int'l: RUO

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Antigen:
Estrogen Receptor Ab-12

Applications:
Immunoprecipitation

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Human, Rat

Isotype:
IgG1

Clone:
6F11

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Steroids Hormones and Growth Factors

Immunogen:
Recombinant full length estrogen receptor protein

Primary or Secondary:
Primary

Img

Fischer Scientific

4542568

Epredia™ Estrogen Receptor Ab-17, R...


Antigen:
Estrogen Receptor Ab-17

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Bovine, Human, Mouse, Porcine, Rabbit, Rat

Isotype:
IgG

Clone:
__

Classification:
Polyclonal

Host Species:
Rabbit

Research Discipline:
Steroids Hormones and Growth Factors

Immunogen:
A synthetic peptide from the N-terminus of human estrogen receptor, alpha protein

Primary or Secondary:
Primary

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4542574

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Antigen:
Estrogen Receptor (SP1)

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
__

Regulatory Status:
IVD

Target Species:
__

Isotype:
__

Clone:
SP1

Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
Steroids Hormones and Growth Factors

Immunogen:
Synthetic peptide derived from C-terminal of human estrogen receptor

Primary or Secondary:
Primary

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4542647

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Antigen:
Factor VIII Related Antigen/von Willebrand Factor Ab-1

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Target Species:
Human

Isotype:
IgG

Clone:
__

Classification:
Polyclonal

Host Species:
Rabbit

Research Discipline:
Hematopoietic

Immunogen:
Purified factor VIII related antigen/von Willebrand factor

Primary or Secondary:
Primary