4542574

Estrogen Receptor (SP1) Rabbit Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Estrogen Receptor (SP1), Rabbit Monoclonal Antibody.

Manufacturer: Fischer Scientific

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Antigen

Estrogen Receptor (SP1)

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Host Species

Rabbit

Research Discipline

Steroids Hormones and Growth Factors

Primary or Secondary

Primary

Clone

SP1

Classification

Monoclonal

Regulatory Status

IVD

Immunogen

Synthetic peptide derived from C-terminal of human estrogen receptor

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Description

  • Description Recognizes a protein of 67 kDa, which is identified as estrogen receptor (ER) alpha
  • The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, and is translated into a protein with six functionally discrete domains, labeled A through F
  • This antibody strongly stains the nucleus of epithelial cells in breast carcinomas
  • The ER is an important regulator of growth and differentiation in the mammary gland
  • Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g
  • tamoxifen) therapy
  • Host Species: Rabbit Clone: SP1 Isotype: IgG Species Reactivity: Human, Mouse and Hamster
  • Others not tested
  • Epitope: C-terminus Immunogen: Synthetic peptide derived from C-terminal of human estrogen receptor Molecular Weight: 67 kDa Positive Control: Breast CA, MCF-7 cells Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunofluorescence (Not verified) Flow Cytometery (Not verified)

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Antigen:
Estrogen Receptor (SP1)

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Host Species:
Rabbit

Research Discipline:
Steroids Hormones and Growth Factors

Primary or Secondary:
Primary

Clone:
SP1

Classification:
Monoclonal

Regulatory Status:
IVD

Immunogen:
Synthetic peptide derived from C-terminal of human estrogen receptor

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Antigen:
Factor VIII Related Antigen/von Willebrand Factor Ab-1

Applications:
Immunohistochemistry (Paraffin)

Host Species:
Rabbit

Research Discipline:
Hematopoietic

Primary or Secondary:
Primary

Clone:
__

Classification:
Polyclonal

Regulatory Status:
IVD

Immunogen:
Purified factor VIII related antigen/von Willebrand factor

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Applications:
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Host Species:
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Research Discipline:
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Primary or Secondary:
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Clone:
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Classification:
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Regulatory Status:
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Antigen:
Factor XIII A Ab-1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Host Species:
Mouse

Research Discipline:
Hematopoietic

Primary or Secondary:
Primary

Clone:
AC-1A1

Classification:
Monoclonal

Regulatory Status:
IVD

Immunogen:
Recombinant protein corresponding to A-subunit of coagulation Factor XIII