4548978
IgA (α-Heavy Chain) Ab-2 Rabbit Polyclonal Antibody, Epredia™
IgA (α-Heavy Chain) Ab-2, Rb PAb is one marker in a comprehensive ab portfolio that addresses all major disease states, ensuring the ideal tests are always available.
Manufacturer: Fischer Scientific
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Antigen
IgA (alpha-Heavy Chain) Ab-2
Classification
Polyclonal
Host Species
Rabbit
Research Discipline
Immunoglobulins
Immunogen
IgA isolated from a pool of normal human sera
Primary or Secondary
Primary
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Regulatory Status
IVD
Target Species
Human
Isotype
IgG
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Description
- The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class
- Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant
- Host Species: Rabbit Isotype: IgG Species Reactivity: Human
- Others not known
- Epitope: Not determined Immunogen: IgA isolated from a pool of normal human sera Molecular Weight: 50kDa Positive Control: Tonsil Cellular Localization: Cytoplasmic Ab-2 recognizes a protein of 50kDa, identified as alpha heavy chain of human immunoglobulins
- It reacts with both IgA1 and IgA2 isotypes
- Ab-2 does not cross-react with γ (IgG), μ (IgM), ε (IgE), or δ (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes
- Ab-2 is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas
- Recommended for: Immunohistochemistry (Formalin/paraffin)
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Antigen: IgA (alpha-Heavy Chain) Ab-2
Classification: Polyclonal
Host Species: Rabbit
Research Discipline: Immunoglobulins
Immunogen: IgA isolated from a pool of normal human sera
Primary or Secondary: Primary
Applications: Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Regulatory Status: IVD
Target Species: Human
Isotype: IgG
Antigen:
IgA (alpha-Heavy Chain) Ab-2
Classification:
Polyclonal
Host Species:
Rabbit
Research Discipline:
Immunoglobulins
Immunogen:
IgA isolated from a pool of normal human sera
Primary or Secondary:
Primary
Applications:
Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Regulatory Status:
IVD
Target Species:
Human
Isotype:
IgG
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