4536540
α-1-Antitrypsin Ab-1 Rabbit Polyclonal Antibody, Epredia™
Obtain accurate, reproducible results with Epredia™ α-1-Antitrypsin Ab-1, Rabbit Polyclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
alpha-1-Antitrypsin Ab-1
Classification
Polyclonal
Host Species
Rabbit
Research Discipline
Enzyme
Immunogen
Purified human serum alpha-1-AT
Primary or Secondary
Primary
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Baboon, Equine, Human, Mink
Isotype
IgG
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Description
- Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung
- In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma
- Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn
- Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation
- Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis
- Host Species: Rabbit Isotype: IgG Species Reactivity: Human, Baboon, Monkey, Horse and Mink
- Does not react with cow, kangaroo, pig, goat, sheep, cat, dog, guinea pig, mouse and chicken
- Others not known
- Immunogen: Purified human serum α-1-AT Positive Control: Tonsil Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin) Note: USA: RUO; Int'l: RUO
Compare Similar Items
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Antigen: alpha-1-Antitrypsin Ab-1
Classification: Polyclonal
Host Species: Rabbit
Research Discipline: Enzyme
Immunogen: Purified human serum alpha-1-AT
Primary or Secondary: Primary
Applications: Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Baboon, Equine, Human, Mink
Isotype: IgG
Antigen:
alpha-1-Antitrypsin Ab-1
Classification:
Polyclonal
Host Species:
Rabbit
Research Discipline:
Enzyme
Immunogen:
Purified human serum alpha-1-AT
Primary or Secondary:
Primary
Applications:
Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Baboon, Equine, Human, Mink
Isotype:
IgG
Antigen: Androgen Receptor Ab-1
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Steroids Hormones and Growth Factors
Immunogen: A synthetic peptide from human AR
Primary or Secondary: Primary
Applications: __
Conjugate: __
Regulatory Status: RUO
Target Species: __
Isotype: __
Antigen:
Androgen Receptor Ab-1
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Steroids Hormones and Growth Factors
Immunogen:
A synthetic peptide from human AR
Primary or Secondary:
Primary
Applications:
__
Conjugate:
__
Regulatory Status:
RUO
Target Species:
__
Isotype:
__
Antigen: __
Classification: __
Host Species: __
Research Discipline: __
Immunogen: __
Primary or Secondary: __
Applications: __
Conjugate: __
Regulatory Status: __
Target Species: __
Isotype: __
Antigen:
__
Classification:
__
Host Species:
__
Research Discipline:
__
Immunogen:
__
Primary or Secondary:
__
Applications:
__
Conjugate:
__
Regulatory Status:
__
Target Species:
__
Isotype:
__
Antigen: E-Cadherin
Classification: Monoclonal
Host Species: Rabbit
Research Discipline: Cancer and Tumor Biology
Immunogen: A synthetic peptide derived from the fifth cadherin domain of human cadherin
Primary or Secondary: Primary
Applications: Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Regulatory Status: IVD
Target Species: __
Isotype: __
Antigen:
E-Cadherin
Classification:
Monoclonal
Host Species:
Rabbit
Research Discipline:
Cancer and Tumor Biology
Immunogen:
A synthetic peptide derived from the fifth cadherin domain of human cadherin
Primary or Secondary:
Primary
Applications:
Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Regulatory Status:
IVD
Target Species:
__
Isotype:
__