46-081-942

CD81 Monoclonal Antibody (1D6-CD81), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 46-081-942-Each-of-1 In Stock ₹ 33,967.32

46-081-942 - Each of 1

₹ 33,967.32

In Stock

Quantity

1

Base Price: ₹ 33,967.32

GST (18%): ₹ 6,114.118

Total Price: ₹ 40,081.438

Antigen

CD81

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P60033

Gene Symbols

CD81

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

975

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

1D6-CD81

Conjugate

PerCP-eFluor 710

Gene

CD81

Gene Alias

26 kDa cell surface protein TAPA-1; CD 81 antigen; Cd81; CD81 antigen; CD81 antigen (target of antiproliferative antibody 1); CD81 molecule; CVID6; S5.7; Tapa1; Tapa-1; Target of the antiproliferative antibody 1; Tetraspanin28; tetraspanin-28; Tspan28; Tspan-28

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • This 1D6-CD81 MAb reacts with human CD81, which is also known as Target of Anti-Proliferative Ab-1 (TAPA-1)
  • A member of the tetraspanin superfamily of transmembrane proteins, CD81 is widely expressed on immune cells such as B, T, and NK cells, monocytes, and eosinophils
  • Studies suggest that the highest expression of CD81 can be found on germinal center B cells
  • This protein can also be detected on non-Hodgkin lymphomas and diffuse large B-cell lymphomas
  • On B cells, CD81 exists in a complex with CD19, CD21, and Leu13
  • CD81 plays a role in segregating the CD19/CD21-B cell receptor complexes to lipid rafts to activate signal transduction
  • Finally, CD81 is a receptor for hepatitis C virus
  • The 1D6 MAb has been reported to induce adhesion and reduce cell proliferation
  • CD81 (TAPA-1, target of anti-proliferative antibody-1) is a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells
  • CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T cells
  • In muscles, CD81 promotes cell fusion and myotube maintenance
  • CD81 has been also identified as a receptor for the hepatitis C virus
  • Like members of the tetraspanin family that include CD9, CD37, CD53, CD63, and CD82, CD81 is a cell-surface proteins that are characterized by the presence of four hydrophobic domains
  • The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility
  • CD81 is a cell surface glycoprotein that is known to complex with integrins
  • CD81 appears to promote muscle cell fusion and support myotube maintenance
  • CD81 associates with CD19, CD21, Leu 13, and integrins on cell membrane and acts as a receptor for the envelope protein E2 of chronic hepatitis C virus
  • Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas
  • CD81 is also localized in the tumor-suppressor gene region and is a candidate gene for malignancies.

Compare Similar Items

Show Difference

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Invitrogen

46-081-942

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Antigen:
CD81

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P60033

Gene Symbols:
CD81

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
975

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
1D6-CD81

Conjugate:
PerCP-eFluor 710

Gene:
CD81

Gene Alias:
26 kDa cell surface protein TAPA-1; CD 81 antigen; Cd81; CD81 antigen; CD81 antigen (target of antiproliferative antibody 1); CD81 molecule; CVID6; S5.7; Tapa1; Tapa-1; Target of the antiproliferative antibody 1; Tetraspanin28; tetraspanin-28; Tspan28; Tspan-28

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Invitrogen

46-088-282

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Antigen:
CD88 (C5aR1)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.:
P30993

Gene Symbols:
C5AR1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12273

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
20/70

Conjugate:
PerCP-eFluor 710

Gene:
C5AR1

Gene Alias:
anaphylatoxin C5a receptor, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin receptor, C5a ligand, C5a Receptor, C5AR, C5a-R, C5AR1, C5r1, Cd88, CD88 antigen, complement C5a receptor, complement C5a receptor 1, complement component 5 receptor 1, complement component 5, receptor 1, complement component 5a receptor 1, D7Msu1

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Img

Invitrogen

46-088-842

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Antigen:
CD88 (C5aR1)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P21730

Gene Symbols:
C5AR1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
728

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
S5/1

Conjugate:
PerCP-eFluor 710

Gene:
C5AR1

Gene Alias:
anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Fischer Scientific

46-090-941

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Antigen:
CD90 (Thy-1)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P04216

Gene Symbols:
Thy1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7070

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
eBio5E10 (5E10)

Conjugate:
PerCP-eFluor 710

Gene:
Thy1

Gene Alias:
CD7; CD90; CDw90; FLJ33325; membrane glycoprotein; T25; Thy 1.2; THY1; Thy-1; Thy-1 antigen; Thy-1 cell surface antigen; thy-1 glycoprotein; thy-1 membrane glycoprotein; Thy-1 protein; Thy-1 T-cell antigen; Thy1.1; Thy1.2; Thy-1.2; thymus cell antigen 1, theta; Thymus cell surface antigen

Host Species:
Mouse

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ