46-581-382
TCR V beta 8.1/8.2 Monoclonal Antibody (KJ16-133 (KJ-16, KJI6, KJ-I6)), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 46-581-382-Each | In Stock | ₹ 30,429.41 |
46-581-382 - Each
In Stock
Quantity
1
Base Price: ₹ 30,429.41
GST (18%): ₹ 5,477.294
Total Price: ₹ 35,906.704
Antigen
TCR V beta 8.1/8.2
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
KJ16-133 (KJ-16, KJI6, KJ-I6)
Conjugate
PerCP-eFluor 710
Gene Alias
TCR V beta8.1; TCR V beta8.2; TCRV beta 8.1; TCRV beta8.1; Vb8.1; Vb8.2; Vbeta8.1; Vbeta8.2
Purification Method
Affinity chromatography
Regulatory Status
RUO
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- This KJ16-133 MAb recognizes mouse T cell receptors (TCR) containing Vbeta 8.1 or 8.2, which is expressed by 15-20% of peripheral T cells in most strains of mice (ie
- Balb/c, AKR, C57BL/6, B10.A) and by a number of T cell hybridomas (ie
- DO-11.10, 3DT-52.5, D1G10G11, SKK-9.11, SKK-45.10, MDK16, S18.4)
- The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response
- TCR recognition of self-peptides has been linked to autoimmune disease
- Mutant self-peptides have been associated with tumors
- Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome
- Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)
- The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease
- Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP)
- A small number of T cells lack both CD4 and CD8 (double negative, DN)
- Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders
- Gamma-delta T cells are primarily found within the epithelium
- They show less TCR diversity and recognize antigens differently than alpha-beta T cells
- Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.
Compare Similar Items
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Antigen: TCR V beta 8.1/8.2
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: KJ16-133 (KJ-16, KJI6, KJ-I6)
Conjugate: PerCP-eFluor 710
Gene Alias: TCR V beta8.1; TCR V beta8.2; TCRV beta 8.1; TCRV beta8.1; Vb8.1; Vb8.2; Vbeta8.1; Vbeta8.2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
TCR V beta 8.1/8.2
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
KJ16-133 (KJ-16, KJI6, KJ-I6)
Conjugate:
PerCP-eFluor 710
Gene Alias:
TCR V beta8.1; TCR V beta8.2; TCRV beta 8.1; TCRV beta8.1; Vb8.1; Vb8.2; Vbeta8.1; Vbeta8.2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: TIM-4
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 54 (RMT4-54)
Conjugate: PerCP-eFluor 710
Gene Alias: B430010N18Rik; RGD1564516; smuckler; soluble TIM 4; Spleen, mucin-containing, knockout of lymphotoxin protein; sTIM 4; T cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim4; TIM-4; TIMD4; TIMD-4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
TIM-4
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
54 (RMT4-54)
Conjugate:
PerCP-eFluor 710
Gene Alias:
B430010N18Rik; RGD1564516; smuckler; soluble TIM 4; Spleen, mucin-containing, knockout of lymphotoxin protein; sTIM 4; T cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim4; TIM-4; TIMD4; TIMD-4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD366 (TIM3)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: RMT3-23
Conjugate: PerCP-eFluor 710
Gene Alias: CD366, FLJ14428, Havcr2, HAVcr-2, Hepatitis A virus cellular receptor 2, hepatitis A virus cellular receptor 2 homolog, kidney injury molecule-3, KIM-3, sCD366, soluble CD366, soluble TIM 3, T cell immunoglobulin mucin 3, T cell immunoglobulin mucin-3, T-cell immunoglobulin and mucin domain containing 3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin family member 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, Tim3, TIM-3, TIMD3, TIMD-3
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD366 (TIM3)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
RMT3-23
Conjugate:
PerCP-eFluor 710
Gene Alias:
CD366, FLJ14428, Havcr2, HAVcr-2, Hepatitis A virus cellular receptor 2, hepatitis A virus cellular receptor 2 homolog, kidney injury molecule-3, KIM-3, sCD366, soluble CD366, soluble TIM 3, T cell immunoglobulin mucin 3, T cell immunoglobulin mucin-3, T-cell immunoglobulin and mucin domain containing 3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin family member 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, Tim3, TIM-3, TIMD3, TIMD-3
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD366 (TIM3)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: RMT3-23
Conjugate: PerCP-eFluor 710
Gene Alias: CD366, FLJ14428, Havcr2, HAVcr-2, Hepatitis A virus cellular receptor 2, hepatitis A virus cellular receptor 2 homolog, kidney injury molecule-3, KIM-3, sCD366, soluble CD366, soluble TIM 3, T cell immunoglobulin mucin 3, T cell immunoglobulin mucin-3, T-cell immunoglobulin and mucin domain containing 3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin family member 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, Tim3, TIM-3, TIMD3, TIMD-3
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD366 (TIM3)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
RMT3-23
Conjugate:
PerCP-eFluor 710
Gene Alias:
CD366, FLJ14428, Havcr2, HAVcr-2, Hepatitis A virus cellular receptor 2, hepatitis A virus cellular receptor 2 homolog, kidney injury molecule-3, KIM-3, sCD366, soluble CD366, soluble TIM 3, T cell immunoglobulin mucin 3, T cell immunoglobulin mucin-3, T-cell immunoglobulin and mucin domain containing 3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin family member 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, Tim3, TIM-3, TIMD3, TIMD-3
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ