46-791-742

CD217 (IL-17Ra) Monoclonal Antibody (424LTS), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 46-791-742-Each-of-1 In Stock ₹ 35,250.72

46-791-742 - Each of 1

₹ 35,250.72

In Stock

Quantity

1

Base Price: ₹ 35,250.72

GST (18%): ₹ 6,345.13

Total Price: ₹ 41,595.85

Antigen

CD217 (IL-17Ra)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

Q96F46

Gene Symbols

Il17ra

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23765

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

424LTS

Conjugate

PerCP-eFluor 710

Gene

Il17ra

Gene Alias

AW538159; CANDF5; CD127; CD217; CDw217; hIL-17R; IL-17 receptor A; IL17R; Il17ra; IL-17RA; interleukin 17 receptor A; interleukin-17 receptor A; MGC10262; VDw217

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Related Products

Img

Invitrogen

50-112-09

--

Img

Invitrogen

48-716-942

--

Img

Invitrogen

50-112-2312

--

Img

Invitrogen

50-100-24

--

Img

Invitrogen

50-112-2393

--

Img

Invitrogen

50-112-3895

--

Img

Invitrogen

50-112-3980

--

Img

Invitrogen

50-057-742

--

Description

  • The 424LTS MAb reacts with and blocks IL-17A binding to human interleukin 17 receptor A (IL-17RA, IL-17R)
  • IL-17RA is a type I membrane protein of approximately 96 kDa (866 amino acids) and is involved in inflammatory responses to IL-17A, IL-17F and IL-17AF heterodimer
  • It forms heterodimeric complexes with several other members of its receptor family, including IL-17RC for IL-17A and IL-17F signaling and IL-17RC for IL-17E (IL-25) signaling
  • IL-17RA is ubiquitously expressed, but in leukocytes its expression is elevated on granulocytes and monocytes
  • Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes
  • It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils
  • IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F
  • IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis
  • Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.

Compare Similar Items

Show Difference

Img

Invitrogen

46-791-742

--


Antigen:
CD217 (IL-17Ra)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q96F46

Gene Symbols:
Il17ra

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23765

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
424LTS

Conjugate:
PerCP-eFluor 710

Gene:
Il17ra

Gene Alias:
AW538159; CANDF5; CD127; CD217; CDw217; hIL-17R; IL-17 receptor A; IL17R; Il17ra; IL-17RA; interleukin 17 receptor A; interleukin-17 receptor A; MGC10262; VDw217

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Tocris Bioscience™

46-831

--


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
1 mg

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Img

R&D Systems™

46-840-9606

--


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
100 μL

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Img

R&D Systems™

46-840-96K

--


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
96 Tests

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__