4697133

CD11C Mouse anti-Human, Brilliant Violet 650, Clone: B-LY6, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD11c

Applications

Flow Cytometry

Conjugate

Brilliant Violet 650

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

ITGAX; AlphaX integrin chain; Axb2; Integrin alpha-X; CR4; Leu M5; SLEB6

Clone

B-LY6

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Slpeen Cells from Human with Hairy Cell Leukemia

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The B-ly6 monoclonal antibody specifically binds to the 150 kDa adhesion glycoprotein CD11c (p150, integrin α chain)
  • CD11c is expressed on dendritic cells, monocytes, macrophages, granulocytes, NK cells and subsets of B and T cells
  • It associates with CD18 to form the CD11c/CD18 complex that binds fibrinogen and has been reported to be a receptor for iC3b and ICAM-1
  • Reports indicate that CD11c/CD18 plays a role as an adhesion molecule that mediates cellular binding to ligands expressed on stimulated epithelium and endothelium
  • The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
  • This dye is a tandem fluorochrome of BD Horizon™ BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 650-nm
  • BD Horizon™ BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20-nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there will bespillover into the APC and Alexa Fluor™ 700 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination.

Compare Similar Items

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Img

Fischer Scientific

4697133

Mouse Monoclonal Antibody...


Antigen:
CD11c

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 650

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
ITGAX; AlphaX integrin chain; Axb2; Integrin alpha-X; CR4; Leu M5; SLEB6

Clone:
B-LY6

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Slpeen Cells from Human with Hairy Cell Leukemia

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

Fischer Scientific

4697134

Mouse Monoclonal Antibody...


Antigen:
CD14

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 650

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
LPS receptor; LPS-R; Myeloid cell-specific leucine-rich glycoprotein

Clone:
M5E2

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Baboon, Canine, Cynomolgus, Human, Rhesus Monkey

Immunogen:
Human CD14 Protein

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Mouse Monoclonal Antibody...


Antigen:
CD14

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 650

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
LPS receptor; LPS-R; Myeloid cell-specific leucine-rich glycoprotein

Clone:
M5E2

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Baboon, Canine, Cynomolgus, Human, Rhesus Monkey

Immunogen:
Human CD14 Protein

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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4697137

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Antigen:
CD14

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 421

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Description:
LPS receptor; LPS-R; Myeloid cell-specific leucine-rich glycoprotein

Clone:
MPHIP9

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human Monocytes

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.