CD154 (CD40 Ligand) Monoclonal Antibody (MR1), eFluor™ 450, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 48-154-182-Each-of-1 | In Stock | ₹ 27,056.00 |
48-154-182 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,056.00
GST (18%): ₹ 4,870.08
Total Price: ₹ 31,926.08
Antigen
CD154 (CD40 Ligand)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P27548
Gene Symbols
CD40LG
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
21947
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
MR1
Conjugate
eFluor 450
Gene
CD40LG
Gene Alias
CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40L; CD40-L; Cd40lg; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5
Host Species
Armenian Hamster
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The MR1 MAb reacts with mouse CD154, a 39 kDa transmembrane glycoprotein also known as CD40 ligand (CD40L)
- CD154 is expressed transiently by activated T cells
- Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction
- CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle
- For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1
- CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells
- The CD40 Ligand stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines
- CD40 Ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes
- It also co-stimulates proliferation of activated T cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.