48-966-880
Ly-6G Monoclonal Antibody (1A8-Ly6g), eFluor™ 450, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 48-966-880-Each-of-1 | In Stock | ₹ 10,951.68 |
48-966-880 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 10,951.68
GST (18%): ₹ 1,971.302
Total Price: ₹ 12,922.982
Antigen
Ly-6G
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P35461
Gene Symbols
Ly6g
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
546644
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
1A8-Ly6g
Conjugate
eFluor 450
Gene
Ly6g
Gene Alias
Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Host Species
Rat
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G, which is also known as Gr-1
- Ly-6G is a 25-kDa GPI protein expressed exclusively by neutrophils
- Studies suggest an important role in neutrophil infiltration, recruitment and migration
- Ly-6G associates with B2 integrins CD11a and CD11b and can attenuate B2 integrin expression and function
- The ligand for Ly-6G is currently unknown
- Unlike the RB6-8C5 antibody, 1A8-Ly6g is reported to only bind to Ly-6G found on neutrophils
- Moreover, 1A8-Ly6g has been used to deplete neutrophils and reported to have antagonist activity
- Applications Reported: This 1A8-Ly6g antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 1A8-Ly6g antibody has been tested by flow cytometric analysis of mouse bone marrow cells
- This can be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- eFluor™ 450 is an alternative to Pacific Blue™
- eFluor™ 450 emits at 445 nm and is excited with the Violet laser (405 nm)
- Please make sure that your instrument is capable of detecting this fluorochrome
- Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser
- Filtration: 0
- Ly6G (Lymphocyte antigen 6 complex locus G6D) is a component of the myeloid differentiation antigen Gr-1, together with Ly6C
- The Ly6G protein has a molecular weight of approximately 21-25 kDa and is expressed by myeloid derived cells in the bone marrow
- Ly6G is a good marker for detection of peripheral neutrophils, monocytes and granulocytes
- Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation
- The physiological role of Ly6G remains unclear but studies have shown its involvement in anti-tumor response, and studies with neutrophils suggest that Ly6G ligation may have an inhibitory effect on local immune responses.
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Antigen: Ly-6G
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P35461
Gene Symbols: Ly6g
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 546644
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 1A8-Ly6g
Conjugate: eFluor 450
Gene: Ly6g
Gene Alias: Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Ly-6G
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P35461
Gene Symbols:
Ly6g
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
546644
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
1A8-Ly6g
Conjugate:
eFluor 450
Gene:
Ly6g
Gene Alias:
Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Ly-6G
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P35461
Gene Symbols: Ly6g
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 546644
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 1A8-Ly6g
Conjugate: eFluor 450
Gene: Ly6g
Gene Alias: Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Ly-6G
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P35461
Gene Symbols:
Ly6g
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
546644
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
1A8-Ly6g
Conjugate:
eFluor 450
Gene:
Ly6g
Gene Alias:
Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Phospho-AKT1 (Ser473)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P31749, P31750
Gene Symbols: AKT1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11651, 207
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: SDRNR
Conjugate: eFluor 450
Gene: AKT1
Gene Alias: Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase; serine-threonine protein kinase; Thymoma viral proto-oncogene; thymoma viral proto-oncogene 1; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene-like protein 1
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Phospho-AKT1 (Ser473)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P31749, P31750
Gene Symbols:
AKT1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11651, 207
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
SDRNR
Conjugate:
eFluor 450
Gene:
AKT1
Gene Alias:
Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase; serine-threonine protein kinase; Thymoma viral proto-oncogene; thymoma viral proto-oncogene 1; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene-like protein 1
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: COX2
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: P35354
Gene Symbols: PTGS2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5743
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: COX 229
Conjugate: eFluor 450
Gene: PTGS2
Gene Alias: COII, COX2, Cox-2, COXII, cyclooxygenase, cyclooxygenase 2, cyclooxygenase 2b, cyclooxygenase-2, Cytochrome c oxidase polypeptide II, Cytochrome c oxidase subunit 2, cytochrome c oxidase subunit II, glucocorticoid-regulated inflammatory cyclooxygenase, Gripghs, hCox-2, Macrophage activation-associated marker protein P71/73, mitochondrially encoded cytochrome c oxidase II, MTCO2, MT-CO2, PES-2, PGG/HS, PGH synthase 2, Pghs2, PGHS-2, Pghs-b, PHS II, PHS-2, prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, prostaglandin-endoperoxide synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Ptgs2, Tis10, TIS10 protein
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
COX2
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
P35354
Gene Symbols:
PTGS2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5743
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
COX 229
Conjugate:
eFluor 450
Gene:
PTGS2
Gene Alias:
COII, COX2, Cox-2, COXII, cyclooxygenase, cyclooxygenase 2, cyclooxygenase 2b, cyclooxygenase-2, Cytochrome c oxidase polypeptide II, Cytochrome c oxidase subunit 2, cytochrome c oxidase subunit II, glucocorticoid-regulated inflammatory cyclooxygenase, Gripghs, hCox-2, Macrophage activation-associated marker protein P71/73, mitochondrially encoded cytochrome c oxidase II, MTCO2, MT-CO2, PES-2, PGG/HS, PGH synthase 2, Pghs2, PGHS-2, Pghs-b, PHS II, PHS-2, prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, prostaglandin-endoperoxide synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Ptgs2, Tis10, TIS10 protein
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ