4986631

CXCR5 Rat anti-Human, BB515, Clone: RF8B2, BD

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CXCR5

Applications

Flow Cytometry

Conjugate

Brilliant Blue 515 (BB515)

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide

Isotype

IgG2b κ

Purification Method

Affinity Purified

Description

CD185; Chemokine C-X-C motif receptor 5; BLR1; MDR-15

Clone

RF8B2

Classification

Monoclonal

Host Species

Rat

Target Species

Human

Immunogen

Human CXCR5

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The RF8B2 monoclonal antibody specifically binds to the human CXC chemokine receptor, CXCR5
  • CXCR5 (also known as CD185, BLR-1 NLR and MDR15), a seven transmembrane, G-protein-coupled receptor, is the specific receptor for CXC chemokine, CXCL13/BLC/BCA-1
  • In peripheral blood, CXCR5 expression is restricted to B lymphocytes and a small subset of CD4+ and CD8+ lymphocytes
  • The restricted expression pattern of CXCR5 on B cells and follicular T helper cells (Tfh) suggests that this receptor functions as a regulator of B and T cell migration
  • Stimulation of T cells with anti-CD3 monoclonal antibody leads to the down-regulation of CXCR5
  • The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences
  • With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (eg, 530/30-nm filter)
  • This dye provides a much brighter alternative to FITC with less spillover into the PE detector.

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Fischer Scientific

4986631

Rat Monoclonal Antibody...


Antigen:
CXCR5

Applications:
Flow Cytometry

Conjugate:
Brilliant Blue 515 (BB515)

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Description:
CD185; Chemokine C-X-C motif receptor 5; BLR1; MDR-15

Clone:
RF8B2

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Human

Immunogen:
Human CXCR5

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Fischer Scientific

4986675

Mouse Monoclonal Antibody...


Antigen:
O-GlcNAc

Applications:
Western Blot, ChIP Assay, ELISA, Immunohistochemistry, Immunocytochemistry

Conjugate:
Unconjugated

Regulatory Status:
RUO

Formulation:
Ascites with 0.1% Sodium Azide

Isotype:
IgG3 κ

Purification Method:
Unpurified

Description:
__

Clone:
HGAC85

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human, All species, Primate

Immunogen:
Heat-killed, pepsin-treated group A streptococci (Streptococcus pyogenes)

Primary or Secondary:
Primary

Content And Storage:
Store at -20C. Avoid freeze-thaw cycles.

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Mouse Monoclonal Antibody...


Antigen:
O-GlcNAc

Applications:
Western Blot, ChIP Assay, ELISA, Immunohistochemistry, Immunocytochemistry

Conjugate:
Unconjugated

Regulatory Status:
RUO

Formulation:
Ascites with 0.1% Sodium Azide

Isotype:
IgG3 κ

Purification Method:
Unpurified

Description:
__

Clone:
HGAC85

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human, All species, Primate

Immunogen:
Heat-killed, pepsin-treated group A streptococci (Streptococcus pyogenes)

Primary or Secondary:
Primary

Content And Storage:
Store at -20C. Avoid freeze-thaw cycles.

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4986677

Mouse Monoclonal Antibody has been ...


Antigen:
O-GlcNAc

Applications:
Western Blot, ChIP Assay, Flow Cytometry, ELISA, Immunohistochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation

Conjugate:
Unconjugated

Regulatory Status:
RUO

Formulation:
__

Isotype:
IgG1

Purification Method:
Protein A purified

Description:
__

Clone:
RL2

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human, Mouse, Rat, Porcine, Bovine, Drosophila, Fish, Hamster, Primate, Virus, Xenopus species

Immunogen:
Pore complex-lamina fraction purified from rat liver nuclear envelopes.

Primary or Secondary:
Primary

Content And Storage:
Store at -20C. Avoid freeze-thaw cycles.