50-105-7414

NOTCH 1 Polyclonal Antibody, Rockland™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-105-7414-Each-of-1 In Stock ₹ 14,374.08

50-105-7414 - Each of 1

₹ 14,374.08

In Stock

Quantity

1

Base Price: ₹ 14,374.08

GST (18%): ₹ 2,587.334

Total Price: ₹ 16,961.414

Antigen

NOTCH 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Notch1

Gene Alias

9930111A19Rik; AOS5; AOVD1; BOS_12152; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); hN1; lin-12; major type A protein; Mis6; Motch; Motch A; mT14; N1; Neurogenic locus notch homolog protein 1; NEXT; NICD; NOTCH; Notch 1; Notch 1 extracellular truncation; Notch 1 intracellular domain; Notch gene homolog 1; Notch homolog 1, translocation-associated; NOTCH1; p300; RP23-306D20.12; RP23-306D20.12-001; TAN1; Translocation-associated notch protein TAN-1; transmembrane receptor Notch1

Host Species

Rabbit

Quantity

25 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Applications

Dot Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

90 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.1% sodium azide; pH 7.2

Gene Accession No.

P46531, Q01705, Q07008

Gene Symbols

Notch1

Immunogen

This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 1 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).

Regulatory Status

RUO

Gene ID (Entrez)

18128, 25496, 4851

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This antiserum is directed against human NOTCH 1
  • Based on the immunogen sequence, we expect this antibody to react as well with mouse and rat NOTCH 1 (100% sequence homology)
  • This antibody reacts with mouse Notch constructs present in lysates of HEK 293 cells
  • Only the cleaved intracellular (activated) form (NICD) is detected
  • No reactivity is detected against mouse N2, N3 or N4
  • The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved form
  • The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region
  • Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures
  • The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1
  • Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).

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Fischer Scientific

50-105-7414

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Antigen:
NOTCH 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Notch1

Gene Alias:
9930111A19Rik; AOS5; AOVD1; BOS_12152; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); hN1; lin-12; major type A protein; Mis6; Motch; Motch A; mT14; N1; Neurogenic locus notch homolog protein 1; NEXT; NICD; NOTCH; Notch 1; Notch 1 extracellular truncation; Notch 1 intracellular domain; Notch gene homolog 1; Notch homolog 1, translocation-associated; NOTCH1; p300; RP23-306D20.12; RP23-306D20.12-001; TAN1; Translocation-associated notch protein TAN-1; transmembrane receptor Notch1

Host Species:
Rabbit

Quantity:
25 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Applications:
Dot Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
90 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P46531, Q01705, Q07008

Gene Symbols:
Notch1

Immunogen:
This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 1 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).

Regulatory Status:
RUO

Gene ID (Entrez):
18128, 25496, 4851

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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Rockland Immunochemicals

50-105-7474

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Antigen:
B-Phycoerythrin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
B-Phycoerythrin

Host Species:
Rabbit

Quantity:
2 mL

Primary or Secondary:
Primary

Target Species:
__

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
75 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
B-Phycoerythrin [Porphyridium cruentum]

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Img

Fischer Scientific

50-105-7532

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Antigen:
SIX3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Six3

Gene Alias:
BOS_11581; E130112M24Rik; Homeobox protein SIX3; HPE2; sine oculis homeobox 3-like protein; Sine oculis homeobox homolog 3; sine oculis homeobox-like protein 3; sine oculis-related homeobox 3; sine oculis-related homeobox 3 homolog; SIX homeobox 3; Six3; Six3a; Six3alpha; Six3b; Six3beta

Host Species:
Guinea Pig

Quantity:
25 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot

Concentration:
0.65 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q62233

Gene Symbols:
Six3

Immunogen:
This Protein A purified antibody was prepared from whole guinea pig serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of mouse Six3 protein.

Regulatory Status:
RUO

Gene ID (Entrez):
20473

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

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50-105-7546

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Antigen:
6X His Epitope Tag

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
6His tag; 6X His; His Tag; Histidine Tag

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
__

Product Type:
Antibody

Applications:
ELISA, Fluorescence Resonance Energy Transfer (FRET), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
HIS Tag antibody was produced in mice by repeated immunizations with 6X His epitope tag peptide H-H-H-H-H-H conjugated to KLH using maleimide.

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid