50-110-15

CD272 (BTLA) Monoclonal Antibody (8F4), PE, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-110-15-Each-of-1 In Stock ₹ 13,090.68

50-110-15 - Each of 1

₹ 13,090.68

In Stock

Quantity

1

Base Price: ₹ 13,090.68

GST (18%): ₹ 2,356.322

Total Price: ₹ 15,447.002

Antigen

CD272 (BTLA)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q7TSA3

Gene Symbols

BTLA

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

208154

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

8F4

Conjugate

PE

Gene

BTLA

Gene Alias

A630002H24; B and T lymphocyte associated; B and T lymphocyte associated protein; B and T lymphocyte attenuator; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; BTLA; BTLA_HUMAN; BTLA1; CD272; CD272 antigen; FLJ16065; MGC129743

Host Species

Mouse

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The BTLA antibody reacts with mouse BTLA, B and T lymphocyte attenuator from both BALB/c and C57Bl/6 strains
  • BTLA is expressed by peripheral lymphocytes, splenic macrophages, developing B cells in the bone marrow and developing T cells in thymus and mature, but not immature bone marrow-derived dendritic cells
  • BTLA is implicated as a negative regulator of the activation and/or function of various hemopoietic cell types
  • It is reported that BTLA binds to B7-H4, but further studies are needed to confirm this interaction
  • Note: The anti-mouse BTLA monoclonal antibody 6F7 is reported to stain CD4+ and CD8+ single-positive (SP) thymocytes (Hurchla et al)
  • However, other anti-mouse BTLA clones generated simultaneously with 6F7 (8F4, 3F9.D12, 6G3 and 6H6) do not stain SP thymocytes
  • It is not understood why there is a discrepancy in thymocyte staining
  • However, in staining of splenocytes and bone marrow cells, clones 8F4, 3F9.D12, 6G3 and 6H6 stain similar populations to 6F7
  • Applications Reported: This 8F4 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 8F4 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This can be used at less than or equal to 0.125 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • BTLA or B and T-lymphocyte attenuator is a member of the co-inhibitory receptors of the CD28 superfamily
  • BTLA is a lymphocyte inhibitory receptor which inhibits lymphocytes during immunes responses
  • BTLA is constitutively expressed on most CD4+ and CD8+ T cells and its expression progressively decreases upon T cell activation
  • It remains expressed on Th1 cells, but not Th2 cells
  • BTLA is a unique co-receptor that interacts with the tumor necrosis factor receptor superfamily member herpesvirus entry mediator (HVEM)
  • This interation is an important pathway regulating lymphocyte activation and/or homeostasis in the immune response.

Compare Similar Items

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Invitrogen

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Antigen:
CD272 (BTLA)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q7TSA3

Gene Symbols:
BTLA

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
208154

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
8F4

Conjugate:
PE

Gene:
BTLA

Gene Alias:
A630002H24; B and T lymphocyte associated; B and T lymphocyte associated protein; B and T lymphocyte attenuator; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; BTLA; BTLA_HUMAN; BTLA1; CD272; CD272 antigen; FLJ16065; MGC129743

Host Species:
Mouse

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

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Invitrogen

50-110-18

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Antigen:
MHC Class I (H-2Kd)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01901, P03991, P04223, P14428

Gene Symbols:
H2-K1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14972

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
SF1-1.1.1

Conjugate:
PE

Gene:
H2-K1

Gene Alias:
class I major histocompatibility antigen H-2Kd; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2 class I histocompatibility antigen, K-W28 alpha chain; H-2K; H2-K; H-2K(B); H-2K(d); H-2K(K); H-2K(Q); H2-K1; histocompatibility 2, K1, K region; K-f; MGC184092; MGC7052; MHC class I antigen; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I heavy chain H2-K; MHC H2-K transplantation antigen

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

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Fischer Scientific

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Antigen:
MHC Class I (H-2Kb)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01901, P03991, P04223, P14428

Gene Symbols:
H2-K1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14972

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
AF6-88.5.5.3

Conjugate:
PE

Gene:
H2-K1

Gene Alias:
class I major histocompatibility antigen H-2Kd; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2 class I histocompatibility antigen, K-W28 alpha chain; H-2K; H2-K; H-2K(B); H-2K(d); H-2K(K); H-2K(Q); H2-K1; histocompatibility 2, K1, K region; K-f; MHC class I antigen; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I heavy chain H2-K; MHC H2-K transplantation antigen

Host Species:
Mouse

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

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Hampton Research

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