50-112-2254

CD103 (Integrin alpha E) Monoclonal Antibody (B-Ly7), PE, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-2254-Each-of-1 In Stock ₹ 26,095.80

50-112-2254 - Each of 1

₹ 26,095.80

In Stock

Quantity

1

Base Price: ₹ 26,095.80

GST (18%): ₹ 4,697.244

Total Price: ₹ 30,793.044

Antigen

CD103 (Integrin alpha E)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P38570

Gene Symbols

Itgae

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3682

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

B-Ly7

Conjugate

PE

Gene

Itgae

Gene Alias

A530055J10; alpha-E1; alpha-M290; aM290; antigen CD103; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; CD103; DC; DCs; HML-1 antigen; human mucosal lymphocyte antigen 1, alpha polypeptide; HUMINAE; integrin alpha E; integrin alpha E, epithelial-associated; integrin alpha E1, epithelial-associated; integrin alpha M290; Integrin alpha-E; Integrin alpha-E heavy chain; Integrin alpha-E light chain; Integrin alpha-IEL; integrin subunit alpha E; integrin, alpha E; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); integrin, alpha E, epithelial-associated; Intregrin alpha E2; Itgae; MGC141996; Mucosal lymphocyte 1 antigen

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The B-Ly7 monoclonal antibody reacts with human CD103, the alpha E integrin
  • CD103 non-covalently associates with integrin beta 7
  • CD103 is expressed mainly on intraepithelial lymphocytes and a small subset of peripheral lymphocytes
  • CD103 is also expressed by hairy cell leukemia (HCL) and by some chronic B cell lymphocytic leukemias
  • In vitro stimulation of human T cells with mitogens induces upregulation of CD103
  • Epithelial cell antigen, E-cadherin, binds to CD103 and mediates homing of lymphocytes to the intestinal epithelium
  • Applications Reported: B-Ly7 has been reported for use in flow cytometric analysis
  • Applications Tested: This B-Ly7 antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells
  • This can be used at 5 μL (0.25 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • CD103 (ITGAE, Integrin alpha E) is molecule that is expressed on mucosa-associated T lymphocytes and activated cells and on subet of TGF beta -1 cells
  • In particular, CD103 includes a 150kDa alpha chain and a 120kDa beta chain
  • CD103 is expressed by 0.5 to 2% of resting lymphocytes in peripheral blood and lymphoid organs
  • CD103 antibody stains a few bone marrow cells and, rarely, peripheral blood lymphocytes
  • CD103 is part of the integrin family which are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain
  • ITGAE encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains
  • In combination with the beta 7 integrin, CD103 protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen
  • CD103 is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation
  • Diseases associated with CD103 dysfunction include hairy cell leukemia and splenic marginal zone lymphoma.

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Show Difference

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Invitrogen

50-112-2254

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Antigen:
CD103 (Integrin alpha E)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P38570

Gene Symbols:
Itgae

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3682

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
B-Ly7

Conjugate:
PE

Gene:
Itgae

Gene Alias:
A530055J10; alpha-E1; alpha-M290; aM290; antigen CD103; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; CD103; DC; DCs; HML-1 antigen; human mucosal lymphocyte antigen 1, alpha polypeptide; HUMINAE; integrin alpha E; integrin alpha E, epithelial-associated; integrin alpha E1, epithelial-associated; integrin alpha M290; Integrin alpha-E; Integrin alpha-E heavy chain; Integrin alpha-E light chain; Integrin alpha-IEL; integrin subunit alpha E; integrin, alpha E; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); integrin, alpha E, epithelial-associated; Intregrin alpha E2; Itgae; MGC141996; Mucosal lymphocyte 1 antigen

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Antigen:
CD106 (VCAM-1)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P29533

Gene Symbols:
VCAM1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22329

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
429

Conjugate:
PE

Gene:
VCAM1

Gene Alias:
adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; Vcam1; Vcam-1; VCAM1B

Host Species:
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Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

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IgG2a κ

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Fischer Scientific

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Antigen:
CD117 (c-Kit)

Classification:
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Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
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Gene Symbols:
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Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16590, 396810

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
2B8

Conjugate:
PE

Gene:
KIT

Gene Alias:
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Porcine

Product Type:
Antibody

Isotype:
IgG2b κ

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Antigen:
CD119 (IFN gamma Receptor 1)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P15261

Gene Symbols:
IFNGR1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15979

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
2E2

Conjugate:
PE

Gene:
IFNGR1

Gene Alias:
antiviral protein, type 2; AVP, type 2; CD119; CD119 antigen; CDw119; Ifgr; IFN-gamma receptor 1; IFN-gammaR; IFN-gamma-R1; IFN-gamma-R-alpha; Ifngr; IFNGR1; IMD27A; IMD27B; immune interferon receptor 1; INF-g receptor; interferon gamma receptor 1; Interferon gamma receptor alpha-chain; interferon-gamma receptor 1; interferon-gamma receptor alpha chain; Nktar

Host Species:
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Quantity:
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Primary or Secondary:
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Target Species:
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Isotype:
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