50-112-2307

CD325 (N-Cadherin) Monoclonal Antibody (8C11), PE, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-2307-Each-of-1 In Stock ₹ 26,780.28

50-112-2307 - Each of 1

₹ 26,780.28

In Stock

Quantity

1

Base Price: ₹ 26,780.28

GST (18%): ₹ 4,820.45

Total Price: ₹ 31,600.73

Antigen

CD325 (N-Cadherin)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P19022

Gene Symbols

CDH2

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1000

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

8C11

Conjugate

PE

Gene

CDH2

Gene Alias

bib; cadherin 2; cadherin 2 L homeolog; cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, neuronal; cadherin 2, type 1 preproprotein; cadherin 2, type 1, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal) L homeolog; cadherin 2, type 1, N-cadherin a (neuronal); Cadherin2; cadherin-2; Cadherin-2A; Cadherin-N; calcium-dependent adhesion protein, neuronal; CD325; CDH2; cdh2.L; cdh2a; cdh2-a; cdh2-b; CDHN; cdhn-a; CDw325; CDw325 antigen; cell adhesion molecule; glass onion; glo; I79_014914; labyrinth; lyr; NCAD; N-Cad; N-cadherin; N-cadherin 1; N-cadherin A; N-cadherin precursor; N-cadherin-2; neural cadherin; Neural cadherin A; neural cadherin-2; neural calcium-dependent cell adhesion molecule; neural-cadherin; pac; Parachute; unnamed protein product; wu:fb47h04; XELAEV_18031953mg; ZNCAD

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The 8C11 monoclonal antibody reacts with human CD325, also known as N-Cadherin
  • CD325 is a 130 kDa member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain
  • CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites
  • Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis
  • Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently dysregulated in cancer cells
  • Applications Reported: This 8C11 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 8C11 antibody has been pre-titrated and tested by flow cytometric analysis of HeLa cells
  • This can be used at 5 μL (0.25 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion
  • Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species
  • N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins
  • The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin
  • Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail
  • The protein functions during gastrulation and is required for establishment of left-right asymmetry.

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Invitrogen

50-112-2307

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Antigen:
CD325 (N-Cadherin)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P19022

Gene Symbols:
CDH2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1000

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
8C11

Conjugate:
PE

Gene:
CDH2

Gene Alias:
bib; cadherin 2; cadherin 2 L homeolog; cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, neuronal; cadherin 2, type 1 preproprotein; cadherin 2, type 1, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal) L homeolog; cadherin 2, type 1, N-cadherin a (neuronal); Cadherin2; cadherin-2; Cadherin-2A; Cadherin-N; calcium-dependent adhesion protein, neuronal; CD325; CDH2; cdh2.L; cdh2a; cdh2-a; cdh2-b; CDHN; cdhn-a; CDw325; CDw325 antigen; cell adhesion molecule; glass onion; glo; I79_014914; labyrinth; lyr; NCAD; N-Cad; N-cadherin; N-cadherin 1; N-cadherin A; N-cadherin precursor; N-cadherin-2; neural cadherin; Neural cadherin A; neural cadherin-2; neural calcium-dependent cell adhesion molecule; neural-cadherin; pac; Parachute; unnamed protein product; wu:fb47h04; XELAEV_18031953mg; ZNCAD

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Antigen:
CD360 (IL-21 Receptor)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9HBE5

Gene Symbols:
Il21r

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50615

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
2SX21R

Conjugate:
PE

Gene:
Il21r

Gene Alias:
CD360; IL-21 receptor; Il21r; IL-21R; interleukin 21 receptor; interleukin-21 receptor; LR-beta; lymphocyte receptor beta; MGC10967; NILR; novel cytokine receptor 8; Novel interleukin receptor; NR8; UNQ3121/PRO10273

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Fischer Scientific

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Antigen:
Mouse IgG2a kappa

Classification:
__

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Control, Flow Cytometry

Clone:
eBM2a

Conjugate:
PE

Gene:
__

Gene Alias:
IgG2; Immunoglobulin G; Immunoglobulin G2; ImmunoglobulinG; ImmunoglobulinG2

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Isotype Control (Primary)

Target Species:
Not Applicable

Product Type:
__

Isotype:
IgG2a κ

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50-112-2316

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Antigen:
EOMES

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
O95936

Gene Symbols:
Eomes

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100622125, 8320

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
WD1928

Conjugate:
PE

Gene:
Eomes

Gene Alias:
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2

Host Species:
Mouse

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Product Type:
Antibody

Isotype:
IgG1 κ