50-112-2489
HELIOS Monoclonal Antibody (22F6), PE, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 50-112-2489-Each | In Stock | ₹ 33,424.01 |
50-112-2489 - Each
In Stock
Quantity
1
Base Price: ₹ 33,424.01
GST (18%): ₹ 6,016.322
Total Price: ₹ 39,440.332
Antigen
HELIOS
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P81183, Q9UKS7
Gene Symbols
IKZF2
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22779, 22807, 488510
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
22F6
Conjugate
PE
Gene
IKZF2
Gene Alias
A730095J18Rik; ANF1A2; Helios; IKAROS family zinc finger 2; IKAROS family zinc finger 2 (Helios); ikaros family zinc finger protein 2; Ikzf2; Zfpn1a2; zinc finger DNA binding protein Helios; zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; Znfn1a2
Host Species
Armenian Hamster
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Canine, Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description: This 22F6 monoclonal antibody reacts with human, mouse and canine Helios
- Helios is a zinc-finger transcription factor first identified for its similarity to Ikaros
- It is expressed in hematopoietic stem cells in both the embryo and adult mice
- While the highest expression is found in regulatory T cells, Helios is not expressed in mature B cells, dendritic cells or myeloid cells
- Helios can form a homodimer as well as heterodimerize with other Ikaros family members to regulate transcription
- Eight isoforms of Helios exist, some of which possess a domit-negative function that has also been found to be upregulated in lymphoid maligcies, including T-acute lymphoblastic leukemia
- 22F6 has been reported to cross react with rat Helios
- Applications Reported: This 22F6 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This 22F6 antibody has been pre-titrated and tested by intracellular staining and flow cytometric analysis of mouse lymph node cell using the Foxp3/Transcription Factor Buffer Set (cat
- 00-5523) and protocol
- Please see Best Protocols Section (Staining intracellular Antigens for Flow Cytometry) for staining protocol (refer to Protocol B: One-step protocol for intracellular (nuclear) proteins)
- This can be used at 5 μL (0.03 μg) per test
- This gene encodes a member of the Ikaros family of zinc-finger proteins
- Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development
- This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development
- Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.
Compare Similar Items
Show Difference
Antigen: HELIOS
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P81183, Q9UKS7
Gene Symbols: IKZF2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22779, 22807, 488510
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 22F6
Conjugate: PE
Gene: IKZF2
Gene Alias: A730095J18Rik; ANF1A2; Helios; IKAROS family zinc finger 2; IKAROS family zinc finger 2 (Helios); ikaros family zinc finger protein 2; Ikzf2; Zfpn1a2; zinc finger DNA binding protein Helios; zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; Znfn1a2
Host Species: Armenian Hamster
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
HELIOS
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P81183, Q9UKS7
Gene Symbols:
IKZF2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22779, 22807, 488510
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
22F6
Conjugate:
PE
Gene:
IKZF2
Gene Alias:
A730095J18Rik; ANF1A2; Helios; IKAROS family zinc finger 2; IKAROS family zinc finger 2 (Helios); ikaros family zinc finger protein 2; Ikzf2; Zfpn1a2; zinc finger DNA binding protein Helios; zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; Znfn1a2
Host Species:
Armenian Hamster
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: CD278 (ICOS)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9WVS0
Gene Symbols: ICOS
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54167
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 7E.17G9
Conjugate: PE
Gene: ICOS
Gene Alias: Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD278 (ICOS)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9WVS0
Gene Symbols:
ICOS
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54167
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
7E.17G9
Conjugate:
PE
Gene:
ICOS
Gene Alias:
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: HLA-G
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P17693
Gene Symbols: HLA-G
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3135
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 87G
Conjugate: PE
Gene: HLA-G
Gene Alias: acrosomal protein SP-10; Acrosomal vesicle protein 1; ACRV1; b2 microglobulin; D11S4365; DADB-15K14.8; HLA class I histocompatibility antigen, alpha chain G; HLA class I molecule; HLA G antigen; HLA-6.0; HLAG; HLA-G; HLA-G histocompatibility antigen, class I, G; LOC768350; major histocompatibility complex, class I, G; MHC class I antigen G; MHC-G; MHCIY; MHC-like class I Y; sHLA-G; Soluble HLA class I histocompatibility antigen, alpha chain G; SP-10; SPACA2; sperm protein 10
Host Species: Mouse
Quantity: 25 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
HLA-G
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P17693
Gene Symbols:
HLA-G
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3135
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
87G
Conjugate:
PE
Gene:
HLA-G
Gene Alias:
acrosomal protein SP-10; Acrosomal vesicle protein 1; ACRV1; b2 microglobulin; D11S4365; DADB-15K14.8; HLA class I histocompatibility antigen, alpha chain G; HLA class I molecule; HLA G antigen; HLA-6.0; HLAG; HLA-G; HLA-G histocompatibility antigen, class I, G; LOC768350; major histocompatibility complex, class I, G; MHC class I antigen G; MHC-G; MHCIY; MHC-like class I Y; sHLA-G; Soluble HLA class I histocompatibility antigen, alpha chain G; SP-10; SPACA2; sperm protein 10
Host Species:
Mouse
Quantity:
25 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: IgM
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P01871
Gene Symbols: IGHM
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3507
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: SA-DA4
Conjugate: PE
Gene: IGHM
Gene Alias: AGM1; IGHM; immunoglobulin heavy constant mu; MU; VH
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
IgM
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P01871
Gene Symbols:
IGHM
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3507
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
SA-DA4
Conjugate:
PE
Gene:
IGHM
Gene Alias:
AGM1; IGHM; immunoglobulin heavy constant mu; MU; VH
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ