50-112-3471

HELIOS Monoclonal Antibody (22F6), PE-Cyanine7, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 50-112-3471-Each-of-1 In Stock ₹ 38,502.00

50-112-3471 - Each of 1

₹ 38,502.00

In Stock

Quantity

1

Base Price: ₹ 38,502.00

GST (18%): ₹ 6,930.36

Total Price: ₹ 45,432.36

Antigen

HELIOS

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P81183, Q9UKS7

Gene Symbols

IKZF2

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22779, 22807, 488510

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

22F6

Conjugate

PE-Cyanine7

Gene

IKZF2

Gene Alias

A730095J18Rik; ANF1A2; Helios; IKAROS family zinc finger 2; IKAROS family zinc finger 2 (Helios); ikaros family zinc finger protein 2; Ikzf2; Zfpn1a2; zinc finger DNA binding protein Helios; zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; Znfn1a2

Host Species

Armenian Hamster

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Description: This 22F6 monoclonal antibody reacts with human, mouse and canine Helios
  • Helios is a zinc-finger transcription factor first identified for its similarity to Ikaros
  • It is expressed in hematopoietic stem cells in both the embryo and adult mice
  • While the highest expression is found in regulatory T cells, Helios is not expressed in mature B cells, dendritic cells or myeloid cells
  • Helios can form a homodimer as well as heterodimerize with other Ikaros family members to regulate transcription
  • Eight isoforms of Helios exist, some of which possess a domit-negative function that has also been found to be upregulated in lymphoid maligcies, including T-acute lymphoblastic leukemia
  • 22F6 has been reported to cross react with rat Helios
  • Applications Reported: This 22F6 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
  • Applications Tested: This 22F6 antibody has been pre-titrated and tested by intracellular staining and flow cytometric analysis of mouse lymph node cells using the Foxp3/Transcription Factor Buffer Set (cat
  • 00-5523) and protocol
  • Please see Best Protocols Section (Staining Intracellular Antigens for Flow Cytometry) for staining protocol (refer to Protocol B: one-step protocol for intracellular (nuclear) proteins)
  • This antibody can be used at 5 μL (0.015 μg) per test
  • HELIOS Monoclonal antibody specifically detects HELIOS in Canine, Human, Mouse samples
  • It is validated for Flow Cytometry.

Compare Similar Items

Show Difference

Img

Invitrogen

50-112-3471

--


Antigen:
HELIOS

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P81183, Q9UKS7

Gene Symbols:
IKZF2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22779, 22807, 488510

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
22F6

Conjugate:
PE-Cyanine7

Gene:
IKZF2

Gene Alias:
A730095J18Rik; ANF1A2; Helios; IKAROS family zinc finger 2; IKAROS family zinc finger 2 (Helios); ikaros family zinc finger protein 2; Ikzf2; Zfpn1a2; zinc finger DNA binding protein Helios; zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; Znfn1a2

Host Species:
Armenian Hamster

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Invitrogen

50-112-3473

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Antigen:
GARP

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
G3XA59

Gene Symbols:
LRRC32

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
434215

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
YGIC86

Conjugate:
PE-Cyanine7

Gene:
LRRC32

Gene Alias:
AI426318; D11S833E; D11S833Eh; D7H11S833E; EG434215; Garp; garpin; Glycoprotein A repetitions predominant; leucine rich repeat containing 32; leucine-rich repeat-containing protein 32; Lrrc32; Transforming growth factor beta activator LRRC32

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

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Invitrogen

50-112-3474

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Antigen:
CD284 (TLR4)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
O00206

Gene Symbols:
TLR4

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7099

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
HTA125

Conjugate:
PE-Cyanine7

Gene:
TLR4

Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Invitrogen

50-112-3475

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Antigen:
CD278 (ICOS)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9WVS0

Gene Symbols:
ICOS

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54167

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
7E.17G9

Conjugate:
PE-Cyanine7

Gene:
ICOS

Gene Alias:
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ