50-112-2768

PSA-NCAM Monoclonal Antibody (12E3), eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-2768-Each-of-1 In Stock ₹ 15,315.24

50-112-2768 - Each of 1

₹ 15,315.24

In Stock

Quantity

1

Base Price: ₹ 15,315.24

GST (18%): ₹ 2,756.743

Total Price: ₹ 18,071.983

Antigen

PSA-NCAM

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P13591, P13595, P13596

Gene Symbols

NCAM1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17967, 24586, 4684

Content And Storage

4° C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone

12E3

Conjugate

Unconjugated

Gene

NCAM1

Gene Alias

antigen recognized by monoclonal antibody 5.1H11; CD56; E-NCAM; MSK39; Ncam; N-CAM; NCAM1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; Polysialylated NCAM; PSA NCAM

Host Species

Mouse

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgM

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Description

  • Description: The monoclonal antibody 12E3 specifically recognizes polysialylated neural cell adhesion molecule (PSA-NCAM) in human, mouse and rat
  • Polysialic acid is a long homopolymer of sialic acid that is negatively charged and is attached to neural cell adhesion molecule (CD56) and serves as a regulator of NCAM function
  • PSA attachment to NCAM is associated with inhibited adhesion of neural cells
  • PSA-NCAM expression is highly regulated and corresponds to specific neural developmental windows in which neural precursors are migrating and during the process of axonal sprouting, guidance, and targeting
  • PSA-NCAM expression is prevalent during development of the brain, but in the adult becomes restricted to regions undergoing self-renewal or exhibiting plasticity such as the olfactory bulb, suprachiasmatic nucleus, hippocampus, hypothalamus, and specific spinal cord nuclei
  • PSA-NCAM is re-expressed during tumorigenesis and is also expressed on cell lines isolated from neuroblastomas and pheochromocytomas
  • Applications Reported: This 12E3 antibody has been reported for use in immunohistochemical staining of frozen tissue sections, immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, microscopy, and immunocytochemistry
  • Applications Tested: This 12E3 antibody has been tested by immunocytochemistry of formaldehyde-fixed PC-12 (rat) cells and can be used at less than or equal to 20 μg/mL
  • Polysialic acid is a long homopolymer of sialic acid that is negatively charged and is attached to neural cell adhesion molecule (CD56) and serves as a regulator of NCAM function
  • PSA attachment to NCAM is associated with inhibited adhesion of neural cells
  • PSA-NCAM expression is highly regulated and corresponds to specific neural developmental windows in which neural precursors are migrating and during the process of axonal sprouting, guidance, and targeting
  • PSA-NCAM expression is prevalent during development of the brain, but in the adult becomes restricted to regions undergoing self-renewal or exhibiting plasticity such as the olfactory bulb, suprachiasmatic nucleus, hippocampus, hypothalamus, and specific spinal cord nuclei
  • PSA-NCAM is re-expressed during tumorigenesis and is also expressed on cell lines isolated from neuroblastomas and pheochromocytomas.

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Show Difference

Img

Fischer Scientific

50-112-2768

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Antigen:
PSA-NCAM

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P13591, P13595, P13596

Gene Symbols:
NCAM1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17967, 24586, 4684

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
12E3

Conjugate:
Unconjugated

Gene:
NCAM1

Gene Alias:
antigen recognized by monoclonal antibody 5.1H11; CD56; E-NCAM; MSK39; Ncam; N-CAM; NCAM1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; Polysialylated NCAM; PSA NCAM

Host Species:
Mouse

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgM

Img

Fischer Scientific

50-112-2769

--


Antigen:
PSA-NCAM

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P13591, P13595, P13596

Gene Symbols:
NCAM1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17967, 24586, 4684

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
12E3

Conjugate:
Unconjugated

Gene:
NCAM1

Gene Alias:
antigen recognized by monoclonal antibody 5.1H11; CD56; E-NCAM; MSK39; Ncam; N-CAM; NCAM1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; Polysialylated NCAM; PSA NCAM

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgM

Img

Invitrogen

50-112-2773

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Antigen:
Fc Receptor Binding Inhibitor

Classification:
__

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
__

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Fc blocking; FcR BI; FcR Inhibitor

Host Species:
Rhesus Monkey

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Rhesus Monkey

Product Type:
__

Isotype:
__

Img

Invitrogen

50-112-2779

--


Antigen:
Estrogen Receptor beta

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q92731

Gene Symbols:
ESR2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2100

Content And Storage:
4° C

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
MC10

Conjugate:
Unconjugated

Gene:
ESR2

Gene Alias:
ER; ER beta; ER[b]; Erb; Erb2; Erbeta; ER-beta; Esr2; ESRB; ESR-BETA; ESTRB; estrogen receptor 2; estrogen receptor 2 (beta); estrogen receptor 2 (ER beta); estrogen receptor 2 beta; estrogen receptor beta; estrogen receptor beta 1 isoform deletion variant; estrogen receptor beta 4; NR3A2; Nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta; steroid receptor

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ