50-112-3008
TGF beta-1,2,3 Monoclonal Antibody (1D11.16.8), Functional Grade, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 50-112-3008-Each | In Stock | ₹ 39,841.01 |
50-112-3008 - Each
In Stock
Quantity
1
Base Price: ₹ 39,841.01
GST (18%): ₹ 7,171.382
Total Price: ₹ 47,012.392
Antigen
TGF beta-1,2,3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.2
Gene Accession No.
P01137, P04202, P17246, P54831
Gene Symbols
TGFB1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100773359, 21803, 403998, 574135, 59086, 7040
Content And Storage
4° C
Form
Liquid
Applications
Functional Assay, Immunohistochemistry (Paraffin), Neutralization
Clone
1D11.16.8
Conjugate
Functional Grade
Gene
TGFB1
Gene Alias
CED; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; tgf beta 1; tgf beta 3; tgf beta1; TGFB; Tgfb1; Tgfb-1; TGFB4; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; TGF-beta4; tissue growth factor-beta4; Transforming growth factor; transforming growth factor beta 1; transforming growth factor beta 4; transforming growth factor beta 4 precursor; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta-1 precursor
Host Species
Mouse
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Canine, Hamster, Human, Mouse, Non-human Primate, Rat, Rhesus Monkey
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Description: The monoclonal antibody 1D11.16.8 recognizes human, mouse, rat, hamster, canine and non-human primate Transforming Growth Factor (TGF) beta 1, 2 and 3
- TGF beta is a pleiotropic cytokine that exists as five isoforms (TGF beta 1-5) that share 70-80% homology with each other
- However, these isoforms are not homologous to TGF alpha
- TGF beta 1 is highly conserved between human, murine, simian, bovine, porcine, and chicken proteins
- TGF beta 1 is the most abundant isoform and is ubiquitously expressed by a variety of cell types, including platelets, macrophages, lymphocytes, endothelial cells, chondrocytes, and leukemic cells
- However, the other isoforms exhibit a more restricted expression pattern
- TGF beta 1 is synthesized as a long precursor polypeptide, which is cleaved to yield the mature protein and the Latency Associated Peptide (LAP)
- LAP and mature TGF beta 1 remain non-covalently associated during secretion, forming homodimers known as the Small Latent Complex (SLC)
- Secretion can be induced by steroids, retinoids, EGF, NGF, vitamin D3, and IL-1
- The bioactivity of mature TGF beta 1 is dependent on its release from LAP by conformational changes and proteolytic processing
- Its activities include inhibition of cell growth in epithelial cells, endothelial cells, fibroblasts, neurons, lymphoid cells, and other hematopoietic cell types
- TGF-beta1, -2, and -3 are a closely related group of proteins (70-80% sequence homology) that are produced by many cell types and function as growth and differentiation factors
- The active forms of TGF-beta1, -2, and -3 are disulfide-linked homodimers.
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Antigen: TGF beta-1,2,3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: P01137, P04202, P17246, P54831
Gene Symbols: TGFB1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100773359, 21803, 403998, 574135, 59086, 7040
Content And Storage: 4° C
Form: Liquid
Applications: Functional Assay, Immunohistochemistry (Paraffin), Neutralization
Clone: 1D11.16.8
Conjugate: Functional Grade
Gene: TGFB1
Gene Alias: CED; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; tgf beta 1; tgf beta 3; tgf beta1; TGFB; Tgfb1; Tgfb-1; TGFB4; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; TGF-beta4; tissue growth factor-beta4; Transforming growth factor; transforming growth factor beta 1; transforming growth factor beta 4; transforming growth factor beta 4 precursor; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta-1 precursor
Host Species: Mouse
Quantity: 500 μg
Primary or Secondary: Primary
Target Species: Canine, Hamster, Human, Mouse, Non-human Primate, Rat, Rhesus Monkey
Product Type: Antibody
Isotype: IgG1
Antigen:
TGF beta-1,2,3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
P01137, P04202, P17246, P54831
Gene Symbols:
TGFB1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100773359, 21803, 403998, 574135, 59086, 7040
Content And Storage:
4° C
Form:
Liquid
Applications:
Functional Assay, Immunohistochemistry (Paraffin), Neutralization
Clone:
1D11.16.8
Conjugate:
Functional Grade
Gene:
TGFB1
Gene Alias:
CED; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; tgf beta 1; tgf beta 3; tgf beta1; TGFB; Tgfb1; Tgfb-1; TGFB4; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; TGF-beta4; tissue growth factor-beta4; Transforming growth factor; transforming growth factor beta 1; transforming growth factor beta 4; transforming growth factor beta 4 precursor; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta-1 precursor
Host Species:
Mouse
Quantity:
500 μg
Primary or Secondary:
Primary
Target Species:
Canine, Hamster, Human, Mouse, Non-human Primate, Rat, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG1
Antigen: Ly-6G
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: P35461
Gene Symbols: Ly6g
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 546644
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Functional Assay
Clone: 1A8-Ly6g
Conjugate: Functional Grade
Gene: Ly6g
Gene Alias: Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Ly-6G
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
P35461
Gene Symbols:
Ly6g
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
546644
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay
Clone:
1A8-Ly6g
Conjugate:
Functional Grade
Gene:
Ly6g
Gene Alias:
Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD369 (Clec7a, Dectin-1)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: Q9BXN2
Gene Symbols: Clec7a
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 64581
Content And Storage: 4° C
Form: Liquid
Applications: Functional Assay
Clone: 15E2
Conjugate: Functional Grade
Gene: Clec7a
Gene Alias: Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082
Host Species: Mouse
Quantity: 500 μg
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD369 (Clec7a, Dectin-1)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
Q9BXN2
Gene Symbols:
Clec7a
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
64581
Content And Storage:
4° C
Form:
Liquid
Applications:
Functional Assay
Clone:
15E2
Conjugate:
Functional Grade
Gene:
Clec7a
Gene Alias:
Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082
Host Species:
Mouse
Quantity:
500 μg
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD178 (Fas Ligand)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: P48023
Gene Symbols: Faslg
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 356
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Neutralization
Clone: NOK-1
Conjugate: Functional Grade
Gene: Faslg
Gene Alias: ADAM10-processed FasL form; ALPS1B; APL; Apoptosis (APO 1) antigen ligand 1; apoptosis (APO-1) antigen ligand 1; Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand); apoptosis antigen ligand; APT1LG1; APTL; CD178; CD178 antigen; CD95 ligand; CD95 ligand protein;Generalized lymphoproliferative disease (Gld); Cd95l; CD95-L; CD95L protein; fas antigen ligand; Fas ligand; Fas ligand (TNF superfamily, member 6); Fasl; Fas-L; FasL ICD; FasL intracellular domain; Faslg; Fas-LG; generalized lymphoproliferative disease; gld; mutant tumor necrosis factor family member 6; Receptor-binding FasL ectodomain; sFasL; Soluble Fas ligand; soluble form; SPA; SPPL2A-processed FasL form; TNFL; Tnfsf6; TNLG1A; Tumor necrosis factor (ligand) superfamily member 6; Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor ligand; tumor necrosis factor ligand 1A; tumor necrosis factor ligand superfamily member 6; Tumor necrosis factor ligand superfamily member 6 (TNFL6 / TNFSF6); Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form
Host Species: Mouse
Quantity: 500 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD178 (Fas Ligand)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
P48023
Gene Symbols:
Faslg
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
356
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Neutralization
Clone:
NOK-1
Conjugate:
Functional Grade
Gene:
Faslg
Gene Alias:
ADAM10-processed FasL form; ALPS1B; APL; Apoptosis (APO 1) antigen ligand 1; apoptosis (APO-1) antigen ligand 1; Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand); apoptosis antigen ligand; APT1LG1; APTL; CD178; CD178 antigen; CD95 ligand; CD95 ligand protein;Generalized lymphoproliferative disease (Gld); Cd95l; CD95-L; CD95L protein; fas antigen ligand; Fas ligand; Fas ligand (TNF superfamily, member 6); Fasl; Fas-L; FasL ICD; FasL intracellular domain; Faslg; Fas-LG; generalized lymphoproliferative disease; gld; mutant tumor necrosis factor family member 6; Receptor-binding FasL ectodomain; sFasL; Soluble Fas ligand; soluble form; SPA; SPPL2A-processed FasL form; TNFL; Tnfsf6; TNLG1A; Tumor necrosis factor (ligand) superfamily member 6; Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor ligand; tumor necrosis factor ligand 1A; tumor necrosis factor ligand superfamily member 6; Tumor necrosis factor ligand superfamily member 6 (TNFL6 / TNFSF6); Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form
Host Species:
Mouse
Quantity:
500 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ