50-112-3466
IRF4 Monoclonal Antibody (3E4), PE-Cyanine7, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-3466-Each-of-1 | In Stock | ₹ 30,887.16 |
50-112-3466 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,887.16
GST (18%): ₹ 5,559.689
Total Price: ₹ 36,446.849
Antigen
IRF4
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q15306, Q64287
Gene Symbols
IRF4
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16364, 3662
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
3E4
Conjugate
PE-Cyanine7
Gene
IRF4
Gene Alias
AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1 κ
Description
- Description: The monoclonal antibody 3E4 reacts with human and mouse interferon regulatory factor 4 (IRF4)
- IRF4 is a 52 kDa transcription factor with roles in B cell, T cell and macrophage function
- In B cells, IRF4 is highly expressed in mature plasma cells and plays a crucial role in their differentiation
- IRF4 has been shown to interact with PU.1 and control the transcription of many B cell-specific genes including Prdm1, which encodes Blimp1
- In T cells, IRF4 has been implicated in regulatory T (Treg), Th2, Th9 and Th17 cell development and function
- This transcription factor is upregulated upon T cell activation and is expressed in mature T cells
- Studies have shown that IRF4 directly induces Blimp1 expression in Tregs, leading to IL-10 expression
- IRF4 has also been demonstrated to be involved in macrophage polarization and regulation
- Lastly, in addition to its roles in normal immune function, IRF4 expression has been reported to be upregulated in many blood-related cancers
- Applications Reported: This 3E4 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This 3E4 antibody has been tested by intracellular staining and flow cytometric analysis of stimulated normal human peripheral blood cells using the Foxp3/Transcription Factor Buffer Set (cat 00-5523) and protocol
- IRF4 Monoclonal antibody specifically detects IRF4 in Human, Mouse samples
- It is validated for Flow Cytometry.
Compare Similar Items
Show Difference
Antigen: IRF4
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q15306, Q64287
Gene Symbols: IRF4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16364, 3662
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 3E4
Conjugate: PE-Cyanine7
Gene: IRF4
Gene Alias: AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
IRF4
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q15306, Q64287
Gene Symbols:
IRF4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16364, 3662
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
3E4
Conjugate:
PE-Cyanine7
Gene:
IRF4
Gene Alias:
AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: HELIOS
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P81183, Q9UKS7
Gene Symbols: IKZF2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22779, 22807, 488510
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 22F6
Conjugate: PE-Cyanine7
Gene: IKZF2
Gene Alias: A730095J18Rik; ANF1A2; Helios; IKAROS family zinc finger 2; IKAROS family zinc finger 2 (Helios); ikaros family zinc finger protein 2; Ikzf2; Zfpn1a2; zinc finger DNA binding protein Helios; zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; Znfn1a2
Host Species: Armenian Hamster
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
HELIOS
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P81183, Q9UKS7
Gene Symbols:
IKZF2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22779, 22807, 488510
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
22F6
Conjugate:
PE-Cyanine7
Gene:
IKZF2
Gene Alias:
A730095J18Rik; ANF1A2; Helios; IKAROS family zinc finger 2; IKAROS family zinc finger 2 (Helios); ikaros family zinc finger protein 2; Ikzf2; Zfpn1a2; zinc finger DNA binding protein Helios; zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; Znfn1a2
Host Species:
Armenian Hamster
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: GARP
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: G3XA59
Gene Symbols: LRRC32
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 434215
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: YGIC86
Conjugate: PE-Cyanine7
Gene: LRRC32
Gene Alias: AI426318; D11S833E; D11S833Eh; D7H11S833E; EG434215; Garp; garpin; Glycoprotein A repetitions predominant; leucine rich repeat containing 32; leucine-rich repeat-containing protein 32; Lrrc32; Transforming growth factor beta activator LRRC32
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
GARP
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
G3XA59
Gene Symbols:
LRRC32
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
434215
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
YGIC86
Conjugate:
PE-Cyanine7
Gene:
LRRC32
Gene Alias:
AI426318; D11S833E; D11S833Eh; D7H11S833E; EG434215; Garp; garpin; Glycoprotein A repetitions predominant; leucine rich repeat containing 32; leucine-rich repeat-containing protein 32; Lrrc32; Transforming growth factor beta activator LRRC32
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD284 (TLR4)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: O00206
Gene Symbols: TLR4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7099
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: HTA125
Conjugate: PE-Cyanine7
Gene: TLR4
Gene Alias: ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD284 (TLR4)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
O00206
Gene Symbols:
TLR4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7099
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
HTA125
Conjugate:
PE-Cyanine7
Gene:
TLR4
Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ