50-112-4887
Ly-6G Monoclonal Antibody (1A8-Ly6g), PE-eFluor™ 610, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-4887-Each-of-1 | In Stock | ₹ 31,999.44 |
50-112-4887 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,999.44
GST (18%): ₹ 5,759.899
Total Price: ₹ 37,759.339
Antigen
Ly-6G
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P35461
Gene Symbols
Ly6g
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
546644
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
1A8-Ly6g
Conjugate
PE-eFluor 610
Gene
Ly6g
Gene Alias
Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Description
- Description: The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G, which is also known as Gr-1
- Ly-6G is a 25-kDa GPI protein expressed exclusively by neutrophils
- Studies suggest an important role in neutrophil infiltration, recruitment and migration
- Ly-6G associates with B2 integrins CD11a and CD11b and can attenuate B2 integrin expression and function
- The ligand for Ly-6G is currently unknown
- Unlike the RB6-8C5 antibody, 1A8-Ly6g is reported to only bind to Ly-6G found on neutrophils
- Moreover, 1A8-Ly6g has been used to deplete neutrophils and reported to have antagonist activity
- Applications Reported: This 1A8-Ly6g antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 1A8-Ly6g antibody has been tested by flow cytometric analysis of mouse bone marrow cells
- This can be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- PE-eFluor™ 610 can be excited with laser lines from 488-561 nm and emits at 607 nm
- We recommend using a 610/20 band pass filter (equivalent to PE-Texas Red™)
- Please make sure that your instrument is capable of detecting this fluorochome
- Ly6G (Lymphocyte antigen 6 complex locus G6D) is a component of the myeloid differentiation antigen Gr-1, together with Ly6C
- The Ly6G protein has a molecular weight of approximately 21-25 kDa and is expressed by myeloid derived cells in the bone marrow
- Ly6G is a good marker for detection of peripheral neutrophils, monocytes and granulocytes
- Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation
- The physiological role of Ly6G remains unclear but studies have shown its involvement in anti-tumor response, and studies with neutrophils suggest that Ly6G ligation may have an inhibitory effect on local immune responses.
Compare Similar Items
Show Difference
Antigen: Ly-6G
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P35461
Gene Symbols: Ly6g
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 546644
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 1A8-Ly6g
Conjugate: PE-eFluor 610
Gene: Ly6g
Gene Alias: Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Ly-6G
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P35461
Gene Symbols:
Ly6g
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
546644
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
1A8-Ly6g
Conjugate:
PE-eFluor 610
Gene:
Ly6g
Gene Alias:
Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: HELIOS
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P81183, Q9UKS7
Gene Symbols: IKZF2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22779, 22807, 488510
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 22F6
Conjugate: PE-eFluor 610
Gene: IKZF2
Gene Alias: A730095J18Rik; ANF1A2; Helios; IKAROS family zinc finger 2; IKAROS family zinc finger 2 (Helios); ikaros family zinc finger protein 2; Ikzf2; Zfpn1a2; zinc finger DNA binding protein Helios; zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; Znfn1a2
Host Species: Armenian Hamster
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
HELIOS
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P81183, Q9UKS7
Gene Symbols:
IKZF2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22779, 22807, 488510
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
22F6
Conjugate:
PE-eFluor 610
Gene:
IKZF2
Gene Alias:
A730095J18Rik; ANF1A2; Helios; IKAROS family zinc finger 2; IKAROS family zinc finger 2 (Helios); ikaros family zinc finger protein 2; Ikzf2; Zfpn1a2; zinc finger DNA binding protein Helios; zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; Znfn1a2
Host Species:
Armenian Hamster
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: CD278 (ICOS)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9Y6W8
Gene Symbols: ICOS
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29851
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: ISA-3
Conjugate: PE-eFluor 610
Gene: ICOS
Gene Alias: Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD278 (ICOS)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9Y6W8
Gene Symbols:
ICOS
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29851
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
ISA-3
Conjugate:
PE-eFluor 610
Gene:
ICOS
Gene Alias:
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD279 (PD-1)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q02242
Gene Symbols: Pdcd1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18566
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: J43
Conjugate: PE-eFluor 610
Gene: Pdcd1
Gene Alias: CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2
Host Species: Armenian Hamster
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CD279 (PD-1)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q02242
Gene Symbols:
Pdcd1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18566
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
J43
Conjugate:
PE-eFluor 610
Gene:
Pdcd1
Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2
Host Species:
Armenian Hamster
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG