50-112-9248
Granzyme A Monoclonal Antibody (GzA-3G8.5), APC, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-9248-Each-of-1 | In Stock | ₹ 32,427.24 |
50-112-9248 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,427.24
GST (18%): ₹ 5,836.903
Total Price: ₹ 38,264.143
Antigen
Granzyme A
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P11032
Gene Symbols
GZMA
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14938
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
GzA-3G8.5
Conjugate
APC
Gene
GZMA
Gene Alias
Autocrine thymic lymphoma granzyme-like serine protease; AW494114; BLT esterase; CTL tryptase; CTLA3; CTLA-3; Cytotoxic T-lymphocyte proteinase 1; Cytotoxic T-lymphocyte-associated serine esterase-3; fragmentin-1; granzyme 1; granzyme A; Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); Granzyme-1; GZMA; H factor; Hanukah factor; Hanukah factor serine protease); Hanukkah factor; Hf; HFSP; Mtsp-1; SE1; serine esterase 1; t cell-specific serine protease 1; TSP1; TSP-1
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Description: This Gza-3G8.5 monoclonal antibody reacts with mouse Granzyme A
- Granzyme A is the most abundantly expressed of the ten granzyme serine proteases that have been identified in mice
- Granzymes are proteins released from the granules of NK cells and cytotoxic T lymphocytes that induce death in target cells by cleavage of intracellular substrates
- They play a critical role in immune defense against viruses, tumors, and intracellular bacteria
- Granzyme A activates caspase-independent cell death pathways morphologically similar to apoptosis and characterized by mitochondrial and DNA damage
- It may also play a role in inflammation, as the precursor form of IL-1 beta (pro-IL-1 beta) is among its target substrates
- Granzyme A shares overlapping substrate specificity with the closely-related Granzyme K, which is believed to account for the minimal decrease in cytotoxicity of Granzyme A-deficient CTLs
- Applications Reported: This GzA-3G8.5 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This GzA-3G8.5 antibody has been tested by intracellular staining followed by flow cytometric analysis of normal mouse splenocytes
- This can be used at less than or equal to 0.125 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells
- They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens
- The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.
Compare Similar Items
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Antigen: Granzyme A
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P11032
Gene Symbols: GZMA
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14938
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: GzA-3G8.5
Conjugate: APC
Gene: GZMA
Gene Alias: Autocrine thymic lymphoma granzyme-like serine protease; AW494114; BLT esterase; CTL tryptase; CTLA3; CTLA-3; Cytotoxic T-lymphocyte proteinase 1; Cytotoxic T-lymphocyte-associated serine esterase-3; fragmentin-1; granzyme 1; granzyme A; Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); Granzyme-1; GZMA; H factor; Hanukah factor; Hanukah factor serine protease); Hanukkah factor; Hf; HFSP; Mtsp-1; SE1; serine esterase 1; t cell-specific serine protease 1; TSP1; TSP-1
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
Granzyme A
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P11032
Gene Symbols:
GZMA
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14938
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
GzA-3G8.5
Conjugate:
APC
Gene:
GZMA
Gene Alias:
Autocrine thymic lymphoma granzyme-like serine protease; AW494114; BLT esterase; CTL tryptase; CTLA3; CTLA-3; Cytotoxic T-lymphocyte proteinase 1; Cytotoxic T-lymphocyte-associated serine esterase-3; fragmentin-1; granzyme 1; granzyme A; Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); Granzyme-1; GZMA; H factor; Hanukah factor; Hanukah factor serine protease); Hanukkah factor; Hf; HFSP; Mtsp-1; SE1; serine esterase 1; t cell-specific serine protease 1; TSP1; TSP-1
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: Armenian Hamster IgG
Classification: __
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: __
Gene Symbols: __
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Control, Flow Cytometry
Clone: eBio299Arm
Conjugate: PE
Gene: __
Gene Alias: IgG; Immunoglobulin G; ImmunoglobulinG
Host Species: Armenian Hamster
Quantity: 200 μg
Primary or Secondary: Isotype Control (Primary)
Target Species: Not Applicable
Product Type: __
Isotype: IgG
Antigen:
Armenian Hamster IgG
Classification:
__
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Control, Flow Cytometry
Clone:
eBio299Arm
Conjugate:
PE
Gene:
__
Gene Alias:
IgG; Immunoglobulin G; ImmunoglobulinG
Host Species:
Armenian Hamster
Quantity:
200 μg
Primary or Secondary:
Isotype Control (Primary)
Target Species:
Not Applicable
Product Type:
__
Isotype:
IgG
Antigen: Mature Macrophage Marker
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: __
Gene Symbols: __
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: eBio25F9 (25F9)
Conjugate: eFluor 660
Gene: __
Gene Alias: ED2-like antigen; Macrophages; Mature Macrophages
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Mature Macrophage Marker
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBio25F9 (25F9)
Conjugate:
eFluor 660
Gene:
__
Gene Alias:
ED2-like antigen; Macrophages; Mature Macrophages
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD278 (ICOS)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9Y6W8
Gene Symbols: ICOS
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29851
Content And Storage: 4° C, do not freeze
Form: Liquid
Applications: Flow Cytometry
Clone: ISA-3
Conjugate: Biotin
Gene: ICOS
Gene Alias: Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD278 (ICOS)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9Y6W8
Gene Symbols:
ICOS
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29851
Content And Storage:
4° C, do not freeze
Form:
Liquid
Applications:
Flow Cytometry
Clone:
ISA-3
Conjugate:
Biotin
Gene:
ICOS
Gene Alias:
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ