50-112-9368

CD357 (AITR/GITR) Monoclonal Antibody (eBioAITR), PE, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-9368-Each-of-1 In Stock ₹ 30,972.72

50-112-9368 - Each of 1

₹ 30,972.72

In Stock

Quantity

1

Base Price: ₹ 30,972.72

GST (18%): ₹ 5,575.09

Total Price: ₹ 36,547.81

Antigen

CD357 (AITR/GITR)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

Q9Y5U5

Gene Symbols

Tnfrsf18

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8784

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

eBioAITR

Conjugate

PE

Gene

Tnfrsf18

Gene Alias

Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The monoclonal antibody reacts with human AITR, Activation Inducible TNFR family member, an approximately 25 kDa member of the TNFR superfamily
  • AITR mRNA is detected in lymph node, peripheral blood leukocytes and weakly in spleen
  • AITR mRNA expression was upregulated within 24 hour on PMA/ionomycin or PHA stimulated PBMC
  • At the protein level, AITR is expressed by a small population of activated PBMC
  • AITR associates with TRAF1, TRAF2 and TRAF3 and induces nuclear factor NF-kappaB activation via TRAF2
  • Recently TL6 (AITRL) has been reported as the ligand for AITR
  • Interaction of AITR with AITRL is important for cross-talk between T lymphocytes and endothelial cells
  • Applications Reported: This eBioAITR antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This eBioAITR antibody has been pre-titrated and tested by flow cytometric analysis of stimulated human peripheral blood mononuclear cells
  • This can be used at 5 μL (0.5 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene
  • It is mapped to 1p36.33
  • This gene encodes a member of the TNF-receptor superfamily
  • The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells
  • Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death
  • Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

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Show Difference

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Invitrogen

50-112-9368

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Antigen:
CD357 (AITR/GITR)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9Y5U5

Gene Symbols:
Tnfrsf18

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8784

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
eBioAITR

Conjugate:
PE

Gene:
Tnfrsf18

Gene Alias:
Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Fischer Scientific

50-112-9370

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Antigen:
CD4

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01730

Gene Symbols:
CD4

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
920

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
RPA-T4

Conjugate:
PE-eFluor 610

Gene:
CD4

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

50-112-9372

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Antigen:
CD23

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P20693

Gene Symbols:
Fcer2a

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14128

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
B3B4

Conjugate:
PE-Cyanine7

Gene:
Fcer2a

Gene Alias:
BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; Fce2; fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; lymphocyte IgE receptor

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Fischer Scientific

50-112-9374

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Antigen:
Mouse IgG1 kappa

Classification:
__

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Control, Flow Cytometry, Immunohistochemistry

Clone:
P3.6.2.8.1

Conjugate:
eFluor 660

Gene:
__

Gene Alias:
IgG1; Igh-4; Ighg1; Immunoglobulin G; Immunoglobulin G1; immunoglobulin heavy constant gamma 1 (G1m marker); ImmunoglobulinG; ImmunoglobulinG1; VH7183

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Isotype Control (Primary)

Target Species:
Not Applicable

Product Type:
__

Isotype:
IgG1 κ