50-112-9764
CD123 Monoclonal Antibody (7G3), eFluor™ 450, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-9764-Each-of-1 | In Stock | ₹ 29,175.96 |
50-112-9764 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,175.96
GST (18%): ₹ 5,251.673
Total Price: ₹ 34,427.633
Antigen
CD123
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P26951
Gene Symbols
IL3RA
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3563
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
7G3
Conjugate
eFluor 450
Gene
IL3RA
Gene Alias
CD123; CD123 antigen; CDw123; Cyrl; cytokine receptor-like protein CYRL; hIL-3Ra; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL3R; IL-3R subunit alpha; Il3ra; IL-3RA; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor subunit alpha; interleukin 3 receptor, alpha; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha; Sut-1
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human, Non-human Primate
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: This 7G3 monoclonal antibody reacts with human and non-human primate CD123, the alpha chain of the IL-3 receptor
- This 60-70 kDa transmembrane protein binds to IL-3 with low affinity by itself, and when associated with CD131 (the common beta chain) binds IL-3 with high affinity
- CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, and megakaryocytes
- In addition, this molecule can be detected on CD34+CD38- hematopoietic stem cells and acute myeloid leukemic (AML) cells
- The 7G3 antibody has been demonstrated to inhibit IL-3-mediated cell proliferation and homing of AML leukemic stem cells
- Crossblocking studies suggest that 7G3 recognizes a different epitope from 6H6
- The 7G3 antibody has been reported to crossreact to chimpanzee, cynomologous monkey, olive baboon, pigtailed macaque, rhesus macaque, and sooty mangabey
- Applications Reported: This 7G3 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 7G3 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
- This can be used at 5 μL (0.5 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- eFluor™ 450 is an alternative to Pacific Blue™
- IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit
- IL-3Ra is responsible for the transmission of signal of Interleukin-3
- IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding
- IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.
Compare Similar Items
Show Difference
Antigen: CD123
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P26951
Gene Symbols: IL3RA
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3563
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 7G3
Conjugate: eFluor 450
Gene: IL3RA
Gene Alias: CD123; CD123 antigen; CDw123; Cyrl; cytokine receptor-like protein CYRL; hIL-3Ra; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL3R; IL-3R subunit alpha; Il3ra; IL-3RA; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor subunit alpha; interleukin 3 receptor, alpha; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha; Sut-1
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD123
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P26951
Gene Symbols:
IL3RA
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3563
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
7G3
Conjugate:
eFluor 450
Gene:
IL3RA
Gene Alias:
CD123; CD123 antigen; CDw123; Cyrl; cytokine receptor-like protein CYRL; hIL-3Ra; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL3R; IL-3R subunit alpha; Il3ra; IL-3RA; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor subunit alpha; interleukin 3 receptor, alpha; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha; Sut-1
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD223 (LAG-3)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q61790
Gene Symbols: LAG3
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16768
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: eBioC9B7W (C9B7W)
Conjugate: FITC
Gene: LAG3
Gene Alias: Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD223 (LAG-3)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q61790
Gene Symbols:
LAG3
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16768
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBioC9B7W (C9B7W)
Conjugate:
FITC
Gene:
LAG3
Gene Alias:
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: Ly-6G
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P35461
Gene Symbols: Ly6g
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 546644
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 1A8-Ly6g
Conjugate: APC
Gene: Ly6g
Gene Alias: Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Ly-6G
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P35461
Gene Symbols:
Ly6g
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
546644
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
1A8-Ly6g
Conjugate:
APC
Gene:
Ly6g
Gene Alias:
Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD71 (Transferrin Receptor)
Classification: Monoclonal
Concentration: __
Formulation: tris with 1% BSA and 0.09% sodium azide; pH 7.3-7.7
Gene Accession No.: P02786
Gene Symbols: TFRC
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7037
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: MRQ-48
Conjugate: Unconjugated
Gene: TFRC
Gene Alias: 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
CD71 (Transferrin Receptor)
Classification:
Monoclonal
Concentration:
__
Formulation:
tris with 1% BSA and 0.09% sodium azide; pH 7.3-7.7
Gene Accession No.:
P02786
Gene Symbols:
TFRC
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7037
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
MRQ-48
Conjugate:
Unconjugated
Gene:
TFRC
Gene Alias:
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1