50-112-9766

CD223 (LAG-3) Monoclonal Antibody (eBioC9B7W (C9B7W)), FITC, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 50-112-9766-Each-of-1 In Stock ₹ 17,967.60

50-112-9766 - Each of 1

₹ 17,967.60

In Stock

Quantity

1

Base Price: ₹ 17,967.60

GST (18%): ₹ 3,234.168

Total Price: ₹ 21,201.768

Antigen

CD223 (LAG-3)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q61790

Gene Symbols

LAG3

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16768

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

eBioC9B7W (C9B7W)

Conjugate

FITC

Gene

LAG3

Gene Alias

Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The eBioC9B7W monoclonal antibody recognizes mouse CD223 (LAG-3, LAG3) protein expressed by activated alpha/beta-TCR bearing T cells, a subset of gamma/delta-TCR bearing T cells and a subset of NK cells
  • CD223 is a 70 kDa type I transmembrane protein with a structure that is similar to CD4
  • However, a soluble form of human CD223 has been detected by ELISA in human serum, and data suggest that mouse CD223 is proteolytically cleaved in the D4 domain
  • This results in a 54 kDa fragment containing all the extracellular domains, and a 16 kDa fragment containing the intracellular and transmembrane domains
  • The 54 kDa can remain membrane-associated or be released as soluble CD223
  • CD223 binds to MHC class II with higher affinity than CD4, and it is thought that this interaction is involved in the negative regulation of T-cell activation and homeostatic proliferation
  • Furthermore, CD223 is expressed by CD4+CD25+ regulatory T cells, and it has been suggested that CD223 may be involved in their regulatory function
  • Applications Reported: This eBioC9B7W (C9B7W) antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This eBioC9B7W (C9B7W) antibody has been tested by flow cytometric analysis of stimulated mouse splenocytes
  • This can be used at less than or equal to 1 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4
  • LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation
  • Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells
  • CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells
  • Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).

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Invitrogen

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Antigen:
CD223 (LAG-3)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q61790

Gene Symbols:
LAG3

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16768

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
eBioC9B7W (C9B7W)

Conjugate:
FITC

Gene:
LAG3

Gene Alias:
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

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Fischer Scientific

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Antigen:
Ly-6G

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P35461

Gene Symbols:
Ly6g

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
546644

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
1A8-Ly6g

Conjugate:
APC

Gene:
Ly6g

Gene Alias:
Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

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Invitrogen

50-112-9770

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Antigen:
CD71 (Transferrin Receptor)

Classification:
Monoclonal

Concentration:
__

Formulation:
tris with 1% BSA and 0.09% sodium azide; pH 7.3-7.7

Gene Accession No.:
P02786

Gene Symbols:
TFRC

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7037

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
MRQ-48

Conjugate:
Unconjugated

Gene:
TFRC

Gene Alias:
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

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Fischer Scientific

50-112-9771

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Antigen:
CD279 (PD-1)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q02242

Gene Symbols:
Pdcd1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18566

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
RMP1-30

Conjugate:
PE

Gene:
Pdcd1

Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ