50-120-53

CD272 (BTLA) Monoclonal Antibody (6F7), Biotin, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 50-120-53-Each In Stock ₹ 10,151.69

50-120-53 - Each

₹ 10,151.69

In Stock

Quantity

1

Base Price: ₹ 10,151.69

GST (18%): ₹ 1,827.304

Total Price: ₹ 11,978.994

Antigen

CD272 (BTLA)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q7TSA3

Gene Symbols

BTLA

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

208154

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

6F7

Conjugate

Biotin

Gene

BTLA

Gene Alias

A630002H24; B and T lymphocyte associated; B and T lymphocyte associated protein; B and T lymphocyte attenuator; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; BTLA; BTLA_HUMAN; BTLA1; CD272; CD272 antigen; FLJ16065; MGC129743

Host Species

Mouse

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The BTLA antibody reacts with mouse BTLA, B and T lymphocyte attenuator
  • BTLA is expressed by peripheral lymphocytes, splenic macrophages, developing B cells in the bone marrow and developing T cells in the thymus and mature, but not immature bone marrow-derived dendritic cells
  • BTLA has been implicated as a negative regulator of the activation and/or function of various hemopoietic cell types
  • It is reported that BTLA binds to B7-H4, but further studies are needed to confirm this interaction
  • Note: The anti-mouse BTLA monoclonal antibody 6F7 is reported to stain CD4^+ and CD8^+ single-positive (SP) thymocytes (Hurchla et al)
  • However, other anti-mouse BTLA clones generated simultaneously with 6F7 (8F4, 3F9.D12, 6G3 and 6H6) do not stain SP thymocytes
  • It is not understood why there is a discrepancy in thymocyte staining however clones 8F4, 3F9.D12, 6G3 and 6H6 stain similar populations to 6F7 in splenocytes and bone marrow cells
  • Applications Reported: This 6F7 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 6F7 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This can be used at less than or equal to 0.125 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • BTLA or B and T-lymphocyte attenuator is a member of the co-inhibitory receptors of the CD28 superfamily
  • BTLA is a lymphocyte inhibitory receptor which inhibits lymphocytes during immunes responses
  • BTLA is constitutively expressed on most CD4+ and CD8+ T cells and its expression progressively decreases upon T cell activation
  • It remains expressed on Th1 cells, but not Th2 cells
  • BTLA is a unique co-receptor that interacts with the tumor necrosis factor receptor superfamily member herpesvirus entry mediator (HVEM)
  • This interation is an important pathway regulating lymphocyte activation and/or homeostasis in the immune response.

Compare Similar Items

Show Difference

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Invitrogen

50-120-53

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Antigen:
CD272 (BTLA)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q7TSA3

Gene Symbols:
BTLA

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
208154

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
6F7

Conjugate:
Biotin

Gene:
BTLA

Gene Alias:
A630002H24; B and T lymphocyte associated; B and T lymphocyte associated protein; B and T lymphocyte attenuator; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; BTLA; BTLA_HUMAN; BTLA1; CD272; CD272 antigen; FLJ16065; MGC129743

Host Species:
Mouse

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Hampton Research

50-120-6

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Img

Invitrogen

50-120-63

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Antigen:
MHC Class I (H-2Kd)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01901, P03991, P04223, P14428

Gene Symbols:
H2-K1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14972

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
SF1-1.1.1

Conjugate:
Biotin

Gene:
H2-K1

Gene Alias:
class I major histocompatibility antigen H-2Kd; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2 class I histocompatibility antigen, K-W28 alpha chain; H-2K; H2-K; H-2K(B); H-2K(d); H-2K(K); H-2K(Q); H2-K1; histocompatibility 2, K1, K region; K-f; MGC184092; MGC7052; MHC class I antigen; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I heavy chain H2-K; MHC H2-K transplantation antigen

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

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Fischer Scientific

50-120-69

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Antigen:
TCR beta

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
0

Gene Symbols:
Tcrb

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21577

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Flow Cytometry

Clone:
H57-597

Conjugate:
Biotin

Gene:
Tcrb

Gene Alias:
bTCR; FLJ22602; MGC117436; MGC22624; MGC23964; MGC71411; T cell receptor beta chain; t-cell antigen receptor; T-cell receptor; TCR beta; Tcra; Tcrb; TCRbeta; TCRD; Tib; TRA

Host Species:
Armenian Hamster

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG