15-223-942

CD223 (LAG-3) Monoclonal Antibody (3DS223H), PE-Cyanine5, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 15-223-942-Each-of-1 In Stock ₹ 27,036.96

15-223-942 - Each of 1

₹ 27,036.96

In Stock

Quantity

1

Base Price: ₹ 27,036.96

GST (18%): ₹ 4,866.653

Total Price: ₹ 31,903.613

Antigen

CD223 (LAG-3)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.

P18627

Gene Symbols

LAG3

Immunogen

hCD223-FC PFA 4%

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

3DS223H

Conjugate

PE-Cyanine5

Gene

LAG3

Gene Alias

Activation-induced cytidine deaminase-linked autoimmunity protein, Aida, CD223, FDC, LAG3, LAG-3, Ly66, lymphocyte activating 3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Secreted lymphocyte activation gene 3 protein, sLAG 3, sLAG3, sLAG-3, soluble LAG 3lymphocyte activating 3, soluble LAG3

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3902

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • Description: This 3DS223H monoclonal antibody recognizes human CD223 also known as Lymphocyte Activation Gene 3 (LAG-3)
  • LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4
  • LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation
  • Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells
  • CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells
  • Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells)
  • This 3DS223H antibody will recognize a formaldehyde-fixed epitope
  • Applications Reported: This 3Ds223H antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 3Ds223H antibody has been pre-diluted and tested by flow cytometric analysis of stimulated normal human peripheral blood cells
  • This may be used at 5 μL (0.25 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
  • Please protect this vial and stained samples from light
  • Fixation: Samples can be stored in IC Fixation Buffer (Product No
  • LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4
  • LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation
  • Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells
  • CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells
  • Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).

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Antigen:
CD223 (LAG-3)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P18627

Gene Symbols:
LAG3

Immunogen:
hCD223-FC PFA 4%

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
3DS223H

Conjugate:
PE-Cyanine5

Gene:
LAG3

Gene Alias:
Activation-induced cytidine deaminase-linked autoimmunity protein, Aida, CD223, FDC, LAG3, LAG-3, Ly66, lymphocyte activating 3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Secreted lymphocyte activation gene 3 protein, sLAG 3, sLAG3, sLAG-3, soluble LAG 3lymphocyte activating 3, soluble LAG3

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3902

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

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Primary or Secondary:
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Target Species:
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T4 DNA Ligase is supplied with a vial of 5X reaction buffer [250 mM Tris-HCl (pH 7.6), 50 mM MgCl2, 5 mM ATP, 5 mM DTT, 25% (w/v) polyethylene glycol-8000]. Store at -20°C.

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Gene Symbols:
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Primary or Secondary:
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Target Species:
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T4 DNA Ligase

Isotype:
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Host Species:
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Purification Method:
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Regulatory Status:
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Gene ID (Entrez):
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Content And Storage:
T4 DNA Ligase is supplied with a vial of 5X reaction buffer [250 mM Tris-HCl (pH 7.6), 50 mM MgCl2, 5 mM ATP, 5 mM DTT, 25% (w/v) polyethylene glycol-8000]. Store at -20°C.

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