50-113-7017

IL-17A Monoclonal Antibody (TC11-8H4), FITC, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-113-7017-Each-of-1 In Stock ₹ 26,694.72

50-113-7017 - Each of 1

₹ 26,694.72

In Stock

Quantity

1

Base Price: ₹ 26,694.72

GST (18%): ₹ 4,805.05

Total Price: ₹ 31,499.77

Antigen

IL-17A

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with <0.1% sodium azide

Gene Accession No.

Q62386

Gene Symbols

IL17A

Immunogen

E. coli-expressed recombinant mouse IL-17 from E. coli-expressed mouse IL-17

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

Applications

ELISA, Flow Cytometry

Clone

TC11-8H4

Conjugate

FITC

Gene

IL17A

Gene Alias

Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A

Host Species

Rat

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

16171

Content And Storage

4° C, store in dark

Form

Liquid

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Description

  • Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection
  • IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217)
  • High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts
  • In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2
  • In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils
  • Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor
  • IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).

Compare Similar Items

Show Difference

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Invitrogen

50-113-7017

--


Antigen:
IL-17A

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
Q62386

Gene Symbols:
IL17A

Immunogen:
E. coli-expressed recombinant mouse IL-17 from E. coli-expressed mouse IL-17

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ELISA, Flow Cytometry

Clone:
TC11-8H4

Conjugate:
FITC

Gene:
IL17A

Gene Alias:
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
16171

Content And Storage:
4° C, store in dark

Form:
Liquid

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Invitrogen

50-113-7019

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Antigen:
CD2

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
P08920

Gene Symbols:
CD2

Immunogen:
mouse CD2 from Crude plasma membranes of ESb cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
12-15

Conjugate:
FITC

Gene:
CD2

Gene Alias:
Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
12481

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Optimize Technologies

50-113-702

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

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Invitrogen

50-113-7020

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Antigen:
CD4

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with proprietary stabilizer and <0.1% sodium azide

Gene Accession No.:
P06332

Gene Symbols:
CD4

Immunogen:
Cloned mouse CTL line V41

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
GK1.5

Conjugate:
APC-Cyanine7

Gene:
CD4

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
12504

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid