50-113-7019

CD2 Monoclonal Antibody (12-15), FITC, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 50-113-7019-Each In Stock ₹ 17,253.17

50-113-7019 - Each

₹ 17,253.17

In Stock

Quantity

1

Base Price: ₹ 17,253.17

GST (18%): ₹ 3,105.571

Total Price: ₹ 20,358.741

Antigen

CD2

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with <0.1% sodium azide

Gene Accession No.

P08920

Gene Symbols

CD2

Immunogen

mouse CD2 from Crude plasma membranes of ESb cells

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

12-15

Conjugate

FITC

Gene

CD2

Gene Alias

Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species

Rat

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

12481

Content And Storage

4° C, store in dark

Form

Liquid

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Description

  • CD2 (LFA-2) is a monomeric surface antigen (MW range 45-58 kDa) of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells
  • CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes and it is also found on some natural killer cells, but not on B lymphocytes
  • Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it
  • The interaction between CD2 and CD58 stabilizes adhesion between T cells and antigen presenting or target cells
  • Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion
  • Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58
  • Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion
  • CD2 deficiency reduces intestinal inflammation and helps to control infection
  • Diseases associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to the absence of the thymus.

Compare Similar Items

Show Difference

Img

Invitrogen

50-113-7019

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Antigen:
CD2

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
P08920

Gene Symbols:
CD2

Immunogen:
mouse CD2 from Crude plasma membranes of ESb cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
12-15

Conjugate:
FITC

Gene:
CD2

Gene Alias:
Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
12481

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Optimize Technologies

50-113-702

--


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Img

Invitrogen

50-113-7020

--


Antigen:
CD4

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with proprietary stabilizer and <0.1% sodium azide

Gene Accession No.:
P06332

Gene Symbols:
CD4

Immunogen:
Cloned mouse CTL line V41

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
GK1.5

Conjugate:
APC-Cyanine7

Gene:
CD4

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
12504

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Invitrogen

50-113-7021

--


Antigen:
CD11a

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with proprietary stabilizer and <0.1% sodium azide

Gene Accession No.:
P20701, P24063

Gene Symbols:
ITGAL

Immunogen:
alpha subunit (Mr 180 kDa) of LFA-1 from Whole BW5147 cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
I21/7

Conjugate:
PE-Cyanine7

Gene:
ITGAL

Gene Alias:
(p180); alpha L integrin; antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; antigen CD11A p180; CD11 antigen-like family member A; CD11a; integrin alpha L; integrin alphaL; integrin alpha-L; integrin alpha-L precursor; integrin gene promoter; integrin subunit alpha L; integrin surface receptor; integrin, alpha L; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte antigen 15; lymphocyte function associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen-1

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
16408, 3683

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid