50-113-8106

CD22 Monoclonal Antibody (2D6), PE, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-113-8106-Each-of-1 In Stock ₹ 31,913.88

50-113-8106 - Each of 1

₹ 31,913.88

In Stock

Quantity

1

Base Price: ₹ 31,913.88

GST (18%): ₹ 5,744.498

Total Price: ₹ 37,658.378

Antigen

CD22

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with <0.1% sodium azide

Gene Accession No.

P35329

Gene Symbols

CD22

Immunogen

Mouse CD22. from Splenic lymphocyte plasma membranes from CBA x C57 F1 mice

Quantity

1 mL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

2D6

Conjugate

PE

Gene

CD22

Gene Alias

A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14

Host Species

Rat

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

12483

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa
  • CD22 is expressed in both the cytoplasm and cell membrane of B-lymphocytes
  • CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen
  • Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 preferentially binds to alpha2,6-linked sialic acid
  • The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface
  • Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling
  • CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 is also positive in diffuse large B-cell lymphoma and nodular lymphocyte predominance Hodgkin’s lymphoma, but negative in classical Hodgkin’s lymphoma.

Compare Similar Items

Show Difference

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Invitrogen

50-113-8106

--


Antigen:
CD22

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
P35329

Gene Symbols:
CD22

Immunogen:
Mouse CD22. from Splenic lymphocyte plasma membranes from CBA x C57 F1 mice

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
2D6

Conjugate:
PE

Gene:
CD22

Gene Alias:
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
12483

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Invitrogen

50-113-8107

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Antigen:
CD23

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 4mg/mL BSA, sucrose and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P20693

Gene Symbols:
Fcer2a

Immunogen:
Mouse CD23.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
B3B4

Conjugate:
APC

Gene:
Fcer2a

Gene Alias:
BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; Fce2; fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; lymphocyte IgE receptor

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
14128

Content And Storage:
4° C

Form:
Liquid

Img

Invitrogen

50-113-8108

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Antigen:
CD45

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P06800

Gene Symbols:
PTPRC

Immunogen:
The CD45 antigen

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
30-F11

Conjugate:
APC

Gene:
PTPRC

Gene Alias:
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
19264

Content And Storage:
4° C

Form:
Liquid

Img

Invitrogen

50-113-8110

--


Antigen:
CD45.2

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
P06800

Gene Symbols:
Ptprc

Immunogen:
B10.S mouse thymocytes and splenocytes.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
104

Conjugate:
FITC

Gene:
Ptprc

Gene Alias:
B220; Cd45; CD45 antigen; CD45R; GP180; LCA; L-CA; leukocyte common antigen; loc; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase, receptor type, C; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
19264

Content And Storage:
4° C, store in dark

Form:
Liquid