17-583-380

Siglec-G Monoclonal Antibody (SH2.1), APC, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 17-583-380-Each-of-1 In Stock ₹ 15,828.60

17-583-380 - Each of 1

₹ 15,828.60

In Stock

Quantity

1

Base Price: ₹ 15,828.60

GST (18%): ₹ 2,849.148

Total Price: ₹ 18,677.748

Antigen

Siglec-G

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q80ZE3

Gene Symbols

Siglecg

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

243958

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

SH2.1

Conjugate

APC

Gene

Siglecg

Gene Alias

9830164H23; A630096C01Rik; mSiglec-G; sialic acid binding Ig-like lectin 10; sialic acid binding Ig-like lectin G; sialic acid-binding Ig-like lectin 10; Sialic acid-binding Ig-like lectin G; Siglec; Siglec 10; Siglec10; Siglec-10; Siglecg; Siglec-G

Host Species

Mouse

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

Related Products

Img

Invitrogen

25-170-282

--

Img

Invitrogen

14-575-937

--

Img

Invitrogen

50-112-8707

--

Img

Invitrogen

17-033-742

--

Img

Invitrogen

50-124-71

--

Img

Invitrogen

50-112-8803

--

Img

Invitrogen

50-113-8106

--

Img

Invitrogen

17-033-942

--

Description

  • The SH2.1 monoclonal antibody reacts with mouse siglec-G, which is also known as sialic acid-binding immunoglobulin-like lectin-G
  • Siglec-G is an inhibitory receptor that is expressed in a B cell-specific manner with B1 B cells expressing the highest levels of siglec-G
  • When overexpressed, siglec-G inhibits B cell receptor-mediated calcium signaling
  • Siglec-G-deficient mice show a massive expansion of the B1a cell population as well as higher titers of natural IgM antibodies
  • Siglec-G-deficient B1a cells show a lower level of spontaneous apoptosis and a prolonged life span, which may result from higher expression levels of the transcription factor NFATc1
  • Siglec-G-dependent negative regulation exists in B1 cells, which may explain the naturally muted signaling response of B1 cells
  • Applications Reported: This SH2.1 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This SH2.1 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This can be used at less than or equal to 0.125 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • Siglec-G is an inhibitory receptor that is expressed in a B cell-specific manner with B1 B cells expressing the highest levels of siglec-G
  • When overexpressed, siglec-G inhibits B cell receptor-mediated calcium signaling
  • Siglec-G-deficient mice show a massive expansion of the B1a cell population as well as higher titers of natural IgM antibodies
  • Siglec-G-deficient B1a cells show a lower level of spontaneous apoptosis and a prolonged life span, which may result from higher expression levels of the transcription factor NFATc1
  • Siglec-G-dependent negative regulation exists in B1 cells, which may explain the naturally muted signaling response of B1 cells.

Compare Similar Items

Show Difference

Img

Invitrogen

17-583-380

--


Antigen:
Siglec-G

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q80ZE3

Gene Symbols:
Siglecg

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
243958

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
SH2.1

Conjugate:
APC

Gene:
Siglecg

Gene Alias:
9830164H23; A630096C01Rik; mSiglec-G; sialic acid binding Ig-like lectin 10; sialic acid binding Ig-like lectin G; sialic acid-binding Ig-like lectin 10; Sialic acid-binding Ig-like lectin G; Siglec; Siglec 10; Siglec10; Siglec-10; Siglecg; Siglec-G

Host Species:
Mouse

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Invitrogen

17-585-982

--


Antigen:
CD369 (Clec7a, Dectin-1)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q6QLQ4

Gene Symbols:
Clec7a

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56644

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
bg1fpj

Conjugate:
APC

Gene:
Clec7a

Gene Alias:
Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Invitrogen

17-598-782

--


Antigen:
CD202b (TIE2)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q02858

Gene Symbols:
TEK

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21687

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
TEK4

Conjugate:
APC

Gene:
TEK

Gene Alias:
AA517024; Angiopoietin-1 receptor; CD202B; CD202b antigen; EC 2.7.10; EC 2.7.10.1; Endothelial tyrosine kinase; endothelial-specific receptor tyrosine kinase; endothelium-specific receptor tyrosine kinase 2; endothelium-specific receptor tyrosine kinase Tie-2; hTIE2; Hyk; mTIE2; p140 TEK; protein-tyrosine kinase Tie2; STK1; Tek; TEK receptor tyrosine kinase; TEK tyrosine kinase, endothelial; TEKT1; Tektin-1; Tie2; tie-2; tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; tyrosine kinases that contain immunoglobulin-like loops and epidermal growth factor-similar domains 2; tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor Tie-2; VMCM; VMCM1

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

MilliporeSigma™

17-600-MI

--


Antigen:
CREBα

Classification:
Monoclonal

Concentration:
__

Formulation:
25 assays per set. Recommended use: ∽10μL antibody per chromatin immunoprecipitation (dependent upon biological context).

Gene Accession No.:
P16220

Gene Symbols:
CREB1, MGC9284, CREB

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
NP_004370

Content And Storage:
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

Form:
Culture Supernatant

Applications:
ChIP Assay, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
__

Host Species:
Rabbit

Quantity:
25 Assays

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
__

Isotype:
IgG