50-113-7110

Bcl-2 Monoclonal Antibody (Bcl2/100), PE, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-113-7110-Each-of-1 In Stock ₹ 25,668.00

50-113-7110 - Each of 1

₹ 25,668.00

In Stock

Quantity

1

Base Price: ₹ 25,668.00

GST (18%): ₹ 4,620.24

Total Price: ₹ 30,288.24

Antigen

Bcl-2, BCL2

Classification

Monoclonal

Conjugate

PE

Gene

Bcl2

Gene Alias

apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

596

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry

Clone

Bcl2/100

Formulation

PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.

P10415

Gene Symbols

Bcl2

Immunogen

Synthetic peptide corresponding to the amino acids 41-54 of human Bcl2

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Related Products

Img

Invitrogen

50-113-7097

--

Img

Invitrogen

14-102-837

--

Img

Invitrogen

14-699-237

--

Img

Invitrogen

50-113-7015

--

Img

Invitrogen

25-669-942

--

Img

Invitrogen

17-903-842

--

Img

Invitrogen

50-112-4615

--

Img

Invitrogen

14-669-937

--

Description

  • BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
  • The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
  • Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
  • Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
  • Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
  • Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
  • In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
  • Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
  • The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.

Compare Similar Items

Show Difference

Img

Invitrogen

50-113-7110

--


Antigen:
Bcl-2, BCL2

Classification:
Monoclonal

Conjugate:
PE

Gene:
Bcl2

Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
Bcl2/100

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P10415

Gene Symbols:
Bcl2

Immunogen:
Synthetic peptide corresponding to the amino acids 41-54 of human Bcl2

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Invitrogen

50-113-7111

--


Antigen:
CD148

Classification:
Monoclonal

Conjugate:
PE

Gene:
PTPRJ

Gene Alias:
AI450271; BET; Byp; CD148; CD148 antigen; colon tumor susceptibility 1; density enhanced phosphatase-1; density-enhanced phosphatase 1; DEP1; DEP-1; HPTP beta-like tyrosine phosphatase; HPTP eta; HPTPeta; human density enhanced phosphatase-1; protein tyrosine phosphatase, receptor type J; protein tyrosine phosphatase, receptor type, J; protein tyrosine phosphatase, receptor type, J polypeptide; protein-tyrosine phosphatase eta; Protein-tyrosine phosphatase receptor type J; Ptpb2; PTPbeta2; Ptprj; Receptor-type tyrosine-protein phosphatase eta; R-PTP-ETA; RPTPJ; R-PTP-J; Scc1; Scc-1; Susceptibility to colon cancer 1; susceptibility to colon cancer 1, mouse, homolog of

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5795

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-CD148/05

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
Q12913

Gene Symbols:
PTPRJ

Immunogen:
Human recombinant CD148 (amino acids 1-444)

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

Invitrogen

50-113-7112

--


Antigen:
CD25

Classification:
Monoclonal

Conjugate:
PerCP

Gene:
IL2RA

Gene Alias:
ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3559

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-181

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P01589

Gene Symbols:
IL2RA

Immunogen:
PHA-activated peripheral blood leucocytes

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Optimize Technologies

50-113-713

--


Antigen:
__

Classification:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Clone:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__