50-113-7522

Perforin Monoclonal Antibody (dG9), Alexa Fluor™ 647, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 50-113-7522-Each-of-1 In Stock ₹ 37,133.04

50-113-7522 - Each of 1

₹ 37,133.04

In Stock

Quantity

1

Base Price: ₹ 37,133.04

GST (18%): ₹ 6,683.947

Total Price: ₹ 43,816.987

Antigen

Perforin

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Gene

PRF1

Gene Alias

Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; OMAK; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; perforin-1; Pfn; PFN1; Pfp; PGFL; PIGF; PIGF-2; PLGF; pore forming protein; pore-forming protein; PRF1; Prf-1; PRF1 (pore forming protein 1); RATCYTA; RP11-710A11.3

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

5551

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry

Clone

dG9

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P14222

Gene Symbols

PRF1

Immunogen

Human Perforin.

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • Perforin is one of the major cytolytic proteins of cytolytic granules
  • Perforin is a cytolytic mediator and is stored in and released by cytoplasmic granules
  • Moreover, perforin is involved in immune defense against tumors and virus infections as mediated by cytotoxic lymphocytes
  • Perforin is a 555 amino acid protein with a 21 amino acid signal peptide, and has a molecular weight of 70 to 75 kD
  • Perforin is a pore forming protein with a mechanism of transmembrane channel formation similar to C9, and homology between perforin and C9 have been demonstrated
  • Studies show that perforin is expressed only in killer cell lines and not in helper T lymphocytes or other tumor cells tested
  • Perforin is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis
  • Defects in the perforin gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood
  • Alternative splicing results in multiple transcript variants of perforin.

Compare Similar Items

Show Difference

Img

Invitrogen

50-113-7522

--


Antigen:
Perforin

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Gene:
PRF1

Gene Alias:
Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; OMAK; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; perforin-1; Pfn; PFN1; Pfp; PGFL; PIGF; PIGF-2; PLGF; pore forming protein; pore-forming protein; PRF1; Prf-1; PRF1 (pore forming protein 1); RATCYTA; RP11-710A11.3

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
5551

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
dG9

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P14222

Gene Symbols:
PRF1

Immunogen:
Human Perforin.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

Invitrogen

50-113-7527

--


Antigen:
LPAM-1

Classification:
Monoclonal

Conjugate:
PE

Gene:
Itgb7

Gene Alias:
CD49 antigen-like family member D; CD49D; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin beta 7; integrin beta-7; Integrin beta-P; Itga4; Itga4B; Itgb7; LPAM subunit alpha; Ly69; lymphocyte Peyer patch adhesion molecules subunit alpha; M290 IEL antigen; VLA; VLA 4; VLA-4 receptor, alpha 4 subunit; VLA4 subunit alpha; VLA-4 subunit alpha

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
16401, 16421

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
DATK32

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
P26011, Q00651

Gene Symbols:
Itga4, Itgb7

Immunogen:
Mouse LPAM-1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Invitrogen

50-113-7528

--


Antigen:
Ly-49F

Classification:
Monoclonal

Conjugate:
FITC

Gene:
Klra6

Gene Alias:
Killer cell lectin-like receptor 6; killer cell lectin-like receptor, subfamily A, member 6; Klra6; Ly-49; Ly49F; Ly-49f; Ly49-f; lymphocyte antigen 49f; T-cell surface glycoprotein Ly-49F

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
16637

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Flow Cytometry

Clone:
HBF-719

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
Q60653

Gene Symbols:
Klra6

Immunogen:
Mouse Ly49F. from CHO-K1 cells transfected with B6 allele of Ly49F gene

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Invitrogen

50-113-7529

--


Antigen:
Ly-49F, Ly49F

Classification:
Monoclonal

Conjugate:
PE

Gene:
Klra6

Gene Alias:
Killer cell lectin-like receptor 6; killer cell lectin-like receptor, subfamily A, member 6; Klra6; Ly-49; Ly49F; Ly-49f; Ly49-f; lymphocyte antigen 49f; T-cell surface glycoprotein Ly-49F

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
16637

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
HBF-719

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
Q60653

Gene Symbols:
Klra6

Immunogen:
Mouse Ly49F. from CHO-K1 cells transfected with B6 allele of Ly49F gene

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ