50-113-7721

CD35 Monoclonal Antibody (E11), PE, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-113-7721-Each-of-1 In Stock ₹ 27,464.76

50-113-7721 - Each of 1

₹ 27,464.76

In Stock

Quantity

1

Base Price: ₹ 27,464.76

GST (18%): ₹ 4,943.657

Total Price: ₹ 32,408.417

Antigen

CD35

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with <0.1% sodium azide

Gene Accession No.

P17927

Gene Symbols

CR1

Immunogen

Human CD35 from Acute monocytic leukemia cells and normal blood monocytes

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Baboon, Chimpanzee, Cynomolgus Monkey, Human, Rhesus Monkey

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

E11

Conjugate

PE

Gene

CR1

Gene Alias

C3 binding protein; C3b/C4b receptor; C3-binding protein; C3BR; C4BR; CD35; CD35 antigen; complement component (3b/4b) receptor 1 (Knops blood group); Complement Component (3b/4b) receptor 1 including Knops blood group system; complement component 3b/4b receptor 1 (Knops blood group); complement receptor type 1; CR1; KN; Knops blood group antigen

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

102117401, 1378, 449643, 718120

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • CD35 (CR1, Complement Receptor 1) is a cell membrane-bound, monomeric glycoprotein and its primary function is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules
  • CD35 protein mediates cellular binding to particles and immune complexes that have activated complement
  • The CD35 complex is four different allotypes (C,A,B,D) C is 160 kDa; A is 190 kDa; B is 220 kDa and D is 250 kDa
  • CD35 is involved in the processing of immune complexes, promoting of binding and phagocytosis of C3b complexes and inhibition of complement activation
  • CD35 is on neutrophils, eosinophils, monocytes, B-cells, some NK-cells, erythrocytes, myeloid leukemias, follicular dendritic reticulum cells and is negative on basophils
  • Decreases in expression of CD35 protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis
  • Mutations in the CD35 gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria
  • Alternate allele-specific splice variants encoding different isoforms of CD35 have been characterized
  • An additional secreted form of CD35 have also been described but has not been fully characterized.

Compare Similar Items

Show Difference

Img

Invitrogen

50-113-7721

--


Antigen:
CD35

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
P17927

Gene Symbols:
CR1

Immunogen:
Human CD35 from Acute monocytic leukemia cells and normal blood monocytes

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Baboon, Chimpanzee, Cynomolgus Monkey, Human, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
E11

Conjugate:
PE

Gene:
CR1

Gene Alias:
C3 binding protein; C3b/C4b receptor; C3-binding protein; C3BR; C4BR; CD35; CD35 antigen; complement component (3b/4b) receptor 1 (Knops blood group); Complement Component (3b/4b) receptor 1 including Knops blood group system; complement component 3b/4b receptor 1 (Knops blood group); complement receptor type 1; CR1; KN; Knops blood group antigen

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
102117401, 1378, 449643, 718120

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Invitrogen

50-113-7723

--


Antigen:
CD74

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
P04233

Gene Symbols:
CD74

Immunogen:
Human CD74 from Cell line SU-DHL-4 nuclei

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
LN2

Conjugate:
FITC

Gene:
CD74

Gene Alias:
CD74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule; Cd74 molecule, major histocompatibility complex, class II invariant chain; class II-associated invariant chain peptide; CLIP; DHLAG; dinucleotide microsatellite; gamma chain of class II antigens; H-2 class II histocompatibility antigen gamma chain; histocompatibility: class II antigens, gamma chain of; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; ia antigen-associated invariant chain; Ia-associated invariant chain; Ia-GAMMA; Ii; invariant polypeptide of major histocompatibility complex, class II antigen-associated; INVG34; MHC class II-associated invariant chain; MHC HLA-DR gamma chain; p33

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
972

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Invitrogen

50-113-7724

--


Antigen:
CD74

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
P04233

Gene Symbols:
CD74

Immunogen:
Human CD74 from Cell line SU-DHL-4 nuclei

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
LN2

Conjugate:
Biotin

Gene:
CD74

Gene Alias:
CD74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule; Cd74 molecule, major histocompatibility complex, class II invariant chain; class II-associated invariant chain peptide; CLIP; DHLAG; dinucleotide microsatellite; gamma chain of class II antigens; H-2 class II histocompatibility antigen gamma chain; histocompatibility: class II antigens, gamma chain of; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; ia antigen-associated invariant chain; Ia-associated invariant chain; Ia-GAMMA; Ii; invariant polypeptide of major histocompatibility complex, class II antigen-associated; INVG34; MHC class II-associated invariant chain; MHC HLA-DR gamma chain; p33

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
972

Content And Storage:
4° C

Form:
Liquid

Img

Optimize Technologies

50-113-773

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