50-115-80

CD49f (Integrin alpha 6) Monoclonal Antibody (eBioGoH3 (GoH3)), Biotin, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 50-115-80-Each In Stock ₹ 20,333.33

50-115-80 - Each

₹ 20,333.33

In Stock

Quantity

1

Base Price: ₹ 20,333.33

GST (18%): ₹ 3,659.999

Total Price: ₹ 23,993.329

Antigen

CD49f (Integrin alpha 6)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P23229, Q61739

Gene Symbols

Itga6

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16403, 3655

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Frozen)

Clone

eBioGoH3 (GoH3)

Conjugate

Biotin

Gene

Itga6

Gene Alias

5033401O05Rik; AI115430; Alpha6p; CD49 antigen-like family member F; CD49f; DKFZp686J01244; FLJ18737; integrin alpha 6; integrin alpha-6; Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; integrin alpha6B; integrin subunit alpha 6; integrin, alpha 6; Itga6; ITGA6B; LOW QUALITY PROTEIN: integrin alpha-6; Processed integrin alpha-6; VLA-6

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • Description: The eBioGoH3 monoclonal antibody reacts with mouse and human CD49f, also known as integrin alpha 6, very late activation antigen 6 (VLA-6 alpha chain), and platelet gpIc
  • CD49f is a 120 kD transmembrane protein
  • CD49f associates with CD29, the integrin beta 1 chain, to form the VLA-6 complex; CD49f also associates with CD104, the integrin beta 4 chain, to form the alpha 6 beta 4 complex
  • CD49f is expressed primarily on T cells, monocytes, platelets, epithelial and endothelial cells
  • CD49f expression has also been found on germinal center B cells
  • The eBioGoH3 antibody is cross-reactive to integrin alpha 6 on human, mouse and bovine cells
  • This antibody has also been reported to have functional activity in blocking the binding of integrin alpha 6 to laminin
  • Applications Reported: This eBioGoH3 (GoH3) antibody has been reported for use in flow cytometric analysis, and immunohistology staining of frozen tissue sections
  • Applications Tested: This eBioGoH3 (GoH3) antibody has been tested by flow cytometric analysis of human peripheral blood cells
  • This can be used at less than or equal to 0.25 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Filtration: 0
  • CDf (Integrin alpha-6, ITGA6) is the integrin alpha chain alpha 6 protein
  • Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain
  • A given chain may combine with multiple partners resulting in different integrins
  • For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6
  • Integrins are known to participate in cell adhesion as well as cell-surface mediated signaling
  • Two transcript variants encoding different isoforms have been found for CDf
  • Functionally, integrins are cell surface receptors that interact with the extracellular matrix and mediate intracellular signals that affect cellular shape, mobility, and progression through the cell cycle in response to the extracellular matrix
  • Integrin receptors are composed of alpha and beta subunits, and form structural and functional linkages between the ECM (extra-cellular matrix) and intracellular cytoskeletal linker proteins
  • Signaling mediated by Intergrin/ECM interactions are also integrated with cellular responses to growth factor signaling to regulate cellular proliferation, cytoskeletal reorganization and other responses necessary for cellular survival
  • CDf is predominantly expressed by epithelia, and plays a critical structural role in the hemidesmosome
  • More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals
  • Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells.

Compare Similar Items

Show Difference

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Invitrogen

50-115-80

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Antigen:
CD49f (Integrin alpha 6)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P23229, Q61739

Gene Symbols:
Itga6

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16403, 3655

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Frozen)

Clone:
eBioGoH3 (GoH3)

Conjugate:
Biotin

Gene:
Itga6

Gene Alias:
5033401O05Rik; AI115430; Alpha6p; CD49 antigen-like family member F; CD49f; DKFZp686J01244; FLJ18737; integrin alpha 6; integrin alpha-6; Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; integrin alpha6B; integrin subunit alpha 6; integrin, alpha 6; Itga6; ITGA6B; LOW QUALITY PROTEIN: integrin alpha-6; Processed integrin alpha-6; VLA-6

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

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Antigen:
CD51/CD61 (Integrin alpha v beta 3)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P05106, P06756

Gene Symbols:
ITGAV, ITGB3

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3685, 3690

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
23C6

Conjugate:
Biotin

Gene:
ITGAV

Gene Alias:
1110004F14Rik; 2610028E01Rik; alpha v integrin; antigen CD61; antigen identified by monoclonal antibody L230; BDPLT16; BDPLT2; Cd51; CD61; D430040G12Rik; Dnmt3l-ps1 pseudogene; GP3A; GPIIIa; GT; INGRB3; integrin; integrin alpha V; integrin alpha-5 beta-3; integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; integrin alphaVbeta3; Integrin beta; integrin beta 3; integrin beta 3 (Cd61); Integrin beta3; integrin beta-3; integrin subunit alpha V; integrin subunit beta 3; integrin, alpha V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGAV; Itgb3; MSK8; platelet gpIIIa; platelet membrane glycoprotein IIIa; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); vitronectin receptor alpha subunit; vitronectin receptor subunit alpha; VNRA; VTNR

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Hampton Research

50-116-0

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Img

Invitrogen

50-116-02

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Antigen:
CD61 (Integrin beta 3)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
O54890

Gene Symbols:
ITGB3

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16416, 29302

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
2C9.G3

Conjugate:
Biotin

Gene:
ITGB3

Gene Alias:
antigen CD61; BDPLT16; BDPLT2; beta3 integrin; CD61; EGK_08849; glycoprotein GPIIIa; glycoprotein IIIa; GP3A; GPIIIa; GT; INGRB3; integrin beta 3; integrin beta 3 (Cd61); integrin beta-3; integrin beta-3 subunit; integrin subunit beta 3; integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGB3; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet gpIIIa; platelet membrane glycoprotein IIIa

Host Species:
Armenian Hamster

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG