50-121-96

IFN gamma Monoclonal Antibody (XMG1.2), Biotin, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-121-96-Each-of-1 In Stock ₹ 27,208.08

50-121-96 - Each of 1

₹ 27,208.08

In Stock

Quantity

1

Base Price: ₹ 27,208.08

GST (18%): ₹ 4,897.454

Total Price: ₹ 32,105.534

Antigen

IFN gamma

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P01580

Gene Symbols

IFNG

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15978

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

ELISA, Flow Cytometry

Clone

XMG1.2

Conjugate

Biotin

Gene

IFNG

Gene Alias

BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Host Species

Rat

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The XMG1.2 antibody reacts with mouse interferon (IFN) gamma
  • The XMG1.2 antibody is a neutralizing antibody
  • Mouse IFN gamma is a 20 kDa factor produced by activated T, B and NK cells, and is an anti-viral and anti-parasitic cytokine
  • IFN gamma, in synergy with other cytokines such as TNF alpha, inhibits proliferation of normal and transformed cells
  • Immunomodulatory effects of IFN gamma are exerted on a wide range of cell types expressing the high affinity receptors for IFN gamma
  • Glycosylation of IFN gamma does not affect its biological activity
  • Applications Reported: XMG1.2 has been reported for use in ELISA and immunoblotting (WB)
  • Applications Tested: The XMG1.2 antibody has been tested by ELISA
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Filtration: 0.2 μm post-manufacturing filtered
  • IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines
  • IFN gamma is a dimeric protein consisting of two 146 amino acid subunits
  • IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa
  • On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation
  • The biological activity of the IFN gamma homodimer is highly species specific
  • Human IFN gamma does not show cross-reactivity with mouse
  • IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes
  • IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines
  • Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway
  • IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma
  • IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN
  • IFN gamma gene mutations are associated with aplastic anemia.

Compare Similar Items

Show Difference

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Invitrogen

50-121-96

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Antigen:
IFN gamma

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01580

Gene Symbols:
IFNG

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15978

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
ELISA, Flow Cytometry

Clone:
XMG1.2

Conjugate:
Biotin

Gene:
IFNG

Gene Alias:
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Host Species:
Rat

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

50-121-99

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Antigen:
IFN gamma

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01579

Gene Symbols:
IFNG

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3458

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
ELISA

Clone:
4S.B3

Conjugate:
Biotin

Gene:
IFNG

Gene Alias:
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Host Species:
Mouse

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Hampton Research

50-122-0

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Img

Fischer Scientific

50-122-00

--


Antigen:
IFN gamma

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01579

Gene Symbols:
IFNG

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3458

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
ELISA

Clone:
4S.B3

Conjugate:
Biotin

Gene:
IFNG

Gene Alias:
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Host Species:
Mouse

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ