50-127-00
CD73 Monoclonal Antibody (eBioTY/11.8 (TY/11.8)), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-127-00-Each-of-1 | In Stock | ₹ 10,780.56 |
50-127-00 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 10,780.56
GST (18%): ₹ 1,940.501
Total Price: ₹ 12,721.061
Antigen
CD73
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q61503
Gene Symbols
NT5E
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23959
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry
Clone
eBioTY/11.8 (TY/11.8)
Conjugate
Unconjugated
Gene
NT5E
Gene Alias
2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; NTE; Purine 5-Prime-Nucleotidase
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1
Description
- Description: eBioTY/11.8 recognizes the with CD73 a 69-kDa GPI-anchored cell-surface protein with ecto-5'-nucleotidase activity
- Expression on myeloid cells (CD11b) is restricted to the bone marrow
- In human CD73 can be induced to secrete a soluble form with IL-2 suggesting a role in mediating activation signals
- Differences between human and mouse CD73 have been reported
- BALB/c mice have more CD4+CD73+ than CD8+CD73+ while the reciprocal is documented in humans
- CD73 is expressed on a subset of lymphocytes and increases during lymphocyte maturation
- Recently it has been found that memory CD4 T cells express and are similar to the uncommitted primed precursor helper cells (Thpp) that can differentiate into Th1 or Th2 cells
- Furthermore CD73 has been found on regulatory T cells
- Applications Reported: This eBioTY/11.8 (TY/11.8) antibody has been reported for use in flow cytometric analysis, and immunohistochemical staining
- Applications Tested: This eBioTY/11.8 (TY/11.8) antibody has been tested by flow cytometric analysis of mouse splenocytes
- This can be used at less than or equal to 0.06 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- CD73 (Ecto-5-prime-nucleotidase, 5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP
- CD73 consists of a dimer of 2 identical 70 kDa subunits bound externally to the plasma membrane by a glycosyl phosphatidyl inositol linkage
- CD73 is used as a marker of lymphocyte differentiation
- Consequently, a deficiency of CD73 occurs in a variety of immunodeficiency diseases
- Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from CD73 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate
- The CD73 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations
- Defects in the CD73 gene can lead to the calcification of joints and arteries, and intestinal tuberculosis
- Two transcript variants encoding different isoforms of CD73 have been found.
Compare Similar Items
Show Difference
Antigen: CD73
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q61503
Gene Symbols: NT5E
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23959
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry
Clone: eBioTY/11.8 (TY/11.8)
Conjugate: Unconjugated
Gene: NT5E
Gene Alias: 2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; NTE; Purine 5-Prime-Nucleotidase
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1
Antigen:
CD73
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q61503
Gene Symbols:
NT5E
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23959
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry
Clone:
eBioTY/11.8 (TY/11.8)
Conjugate:
Unconjugated
Gene:
NT5E
Gene Alias:
2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; NTE; Purine 5-Prime-Nucleotidase
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1
Antigen: CD74
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P04233
Gene Symbols: CD74
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 972
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: VIC-Y1
Conjugate: Unconjugated
Gene: CD74
Gene Alias: CD74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule; Cd74 molecule, major histocompatibility complex, class II invariant chain; class II-associated invariant chain peptide; CLIP; DHLAG; dinucleotide microsatellite; gamma chain of class II antigens; H-2 class II histocompatibility antigen gamma chain; histocompatibility: class II antigens, gamma chain of; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; ia antigen-associated invariant chain; Ia-associated invariant chain; Ia-GAMMA; Ii; invariant polypeptide of major histocompatibility complex, class II antigen-associated; INVG34; MHC class II-associated invariant chain; MHC HLA-DR gamma chain; p33
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
CD74
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P04233
Gene Symbols:
CD74
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
972
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
VIC-Y1
Conjugate:
Unconjugated
Gene:
CD74
Gene Alias:
CD74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule; Cd74 molecule, major histocompatibility complex, class II invariant chain; class II-associated invariant chain peptide; CLIP; DHLAG; dinucleotide microsatellite; gamma chain of class II antigens; H-2 class II histocompatibility antigen gamma chain; histocompatibility: class II antigens, gamma chain of; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; ia antigen-associated invariant chain; Ia-associated invariant chain; Ia-GAMMA; Ii; invariant polypeptide of major histocompatibility complex, class II antigen-associated; INVG34; MHC class II-associated invariant chain; MHC HLA-DR gamma chain; p33
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: CD79b
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P40259
Gene Symbols: Cd79b
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 974
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Western Blot
Clone: CB3-1
Conjugate: Unconjugated
Gene: Cd79b
Gene Alias: AGM6; B29; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; CD79; CD79b; CD79B antigen; CD79b molecule; Cd79b molecule, immunoglobulin-associated beta; Ig beta; IGB; Igbeta; Ig-beta; Immunoglobulin-associated B29 protein; immunoglobulin-associated beta; RP23-418O11.7
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
CD79b
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P40259
Gene Symbols:
Cd79b
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
974
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Clone:
CB3-1
Conjugate:
Unconjugated
Gene:
Cd79b
Gene Alias:
AGM6; B29; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; CD79; CD79b; CD79B antigen; CD79b molecule; Cd79b molecule, immunoglobulin-associated beta; Ig beta; IGB; Igbeta; Ig-beta; Immunoglobulin-associated B29 protein; immunoglobulin-associated beta; RP23-418O11.7
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: CD83
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O88324
Gene Symbols: CD83
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12522
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: Michel-17 (Michel17)
Conjugate: Unconjugated
Gene: CD83
Gene Alias: B-cell activation protein; BL11; CD antigen CD83; CD83; CD83 antigen; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); CD83 molecule; cell surface protein HB15; cell-surface glycoprotein; HB15; hCD83; mCD83
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1
Antigen:
CD83
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O88324
Gene Symbols:
CD83
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12522
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
Michel-17 (Michel17)
Conjugate:
Unconjugated
Gene:
CD83
Gene Alias:
B-cell activation protein; BL11; CD antigen CD83; CD83; CD83 antigen; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); CD83 molecule; cell surface protein HB15; cell-surface glycoprotein; HB15; hCD83; mCD83
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1