50-129-77
CD205 Monoclonal Antibody (MG38), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-129-77-Each-of-1 | In Stock | ₹ 28,577.04 |
50-129-77 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,577.04
GST (18%): ₹ 5,143.867
Total Price: ₹ 33,720.907
Antigen
CD205
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
O60449
Gene Symbols
LY75
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4065
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone
MG38
Conjugate
Unconjugated
Gene
LY75
Gene Alias
CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Description: The MG38 monoclonal antibody reacts with human CD205, also known as DEC-205, an integral membrane protein homologous to the macrophage mannose receptor
- CD205 is an endocytic dendritic receptor that mediates efficient processing and presentation of antigens on MHC class II productions in vivo
- CD205 is highly expressed by dendritic cells (DCs) within the T cell areas of lymphoid tissues, particularly on CD8^+ DCs that are believed to play a role in cross-priming
- Expression of CD205 is detected with this antibody at high intensity on in vitro derived mature human DCs (mDC) and at intermediate intensity on immature human DCs (iDC)
- All leukocytes from peripheral blood show a degree of staining with this mAb that can be minimized by using very low concentrations of MG38
- Applications Reported: The MG38 antibody has been reported for use in flow cytometric analysis, immunoprecipitation, and immunohistochemical staining of frozen tissue sections
- Applications Tested: This MG38 antibody has been tested by flow cytometric analysis of in vitro derived human dendritic cells and peripheral blood cells
- This can be used at less than or equal to 0.03 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity
- CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells
- CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region
- Further, CD205 also prompts the reduced proliferation of B lymphocytes
- Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
Compare Similar Items
Show Difference
Antigen: CD205
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O60449
Gene Symbols: LY75
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4065
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: MG38
Conjugate: Unconjugated
Gene: LY75
Gene Alias: CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD205
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O60449
Gene Symbols:
LY75
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4065
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
MG38
Conjugate:
Unconjugated
Gene:
LY75
Gene Alias:
CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ
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